Investigating the Anti-Aging Effects of Caviar Oil on Human Skin

As the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing...

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Veröffentlicht in:In vivo (Athens) 2023-09, Vol.37 (5), p.2078-2091
Hauptverfasser: LE, LINH THI THUY, KIM, BAEK-KYU, CHIEN, PHAM NGOC, CHOI, KEON-WOO, KIM, HONG-BIN, HWANG, UI-JAE, HAN, HYO SUN, HEO, CHAN-YEONG
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container_title In vivo (Athens)
container_volume 37
creator LE, LINH THI THUY
KIM, BAEK-KYU
CHIEN, PHAM NGOC
CHOI, KEON-WOO
KIM, HONG-BIN
HWANG, UI-JAE
HAN, HYO SUN
HEO, CHAN-YEONG
description As the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.BACKGROUND/AIMAs the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.An in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.MATERIALS AND METHODSAn in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical s
doi_str_mv 10.21873/invivo.13305
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However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.BACKGROUND/AIMAs the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.An in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.MATERIALS AND METHODSAn in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.In vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.RESULTSIn vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.Caviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.CONCLUSIONCaviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.</description><identifier>ISSN: 0258-851X</identifier><identifier>ISSN: 1791-7549</identifier><identifier>EISSN: 1791-7549</identifier><identifier>DOI: 10.21873/invivo.13305</identifier><identifier>PMID: 37652485</identifier><language>eng</language><publisher>International Institute of Anticancer Research</publisher><ispartof>In vivo (Athens), 2023-09, Vol.37 (5), p.2078-2091</ispartof><rights>Copyright © 2023, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.</rights><rights>Copyright 2023, International Institute of Anticancer Research 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500528/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500528/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>LE, LINH THI THUY</creatorcontrib><creatorcontrib>KIM, BAEK-KYU</creatorcontrib><creatorcontrib>CHIEN, PHAM NGOC</creatorcontrib><creatorcontrib>CHOI, KEON-WOO</creatorcontrib><creatorcontrib>KIM, HONG-BIN</creatorcontrib><creatorcontrib>HWANG, UI-JAE</creatorcontrib><creatorcontrib>HAN, HYO SUN</creatorcontrib><creatorcontrib>HEO, CHAN-YEONG</creatorcontrib><title>Investigating the Anti-Aging Effects of Caviar Oil on Human Skin</title><title>In vivo (Athens)</title><description>As the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.BACKGROUND/AIMAs the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.An in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.MATERIALS AND METHODSAn in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.In vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.RESULTSIn vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.Caviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.CONCLUSIONCaviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.</description><issn>0258-851X</issn><issn>1791-7549</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpVkMFLwzAUh4Mobk6P3nv00vle0jTpSceYbjDYQQVvIUvTLtqls2kL_vfObQieHo_34_vxPkJuEcYUpWD3zveur8fIGPAzMkSRYSx4kp2TIVAuY8nxfUCuQvgASAUAvSQDJlJOE8mH5HHhextaV-rW-TJqNzaa-NbFk_J3nRWFNW2I6iKa6t7pJlq5Kqp9NO-22kcvn85fk4tCV8HenOaIvD3NXqfzeLl6Xkwny9gwim2cGyF5sgYOGqSROWqbCUoZChBZQlOraYYJFIIiSwFTbdaaC5R2LRCL3LAReThyd916a3NjfdvoSu0at9XNt6q1U_8v3m1UWfcK953AqdwT7k6Epv7q9k-rrQvGVpX2tu6CojKFBBhSsY_Gx6hp6hAaW_z1IKiDdnXUrg7a2Q8UuHRa</recordid><startdate>20230901</startdate><enddate>20230901</enddate><creator>LE, LINH THI THUY</creator><creator>KIM, BAEK-KYU</creator><creator>CHIEN, PHAM NGOC</creator><creator>CHOI, KEON-WOO</creator><creator>KIM, HONG-BIN</creator><creator>HWANG, UI-JAE</creator><creator>HAN, HYO SUN</creator><creator>HEO, CHAN-YEONG</creator><general>International Institute of Anticancer Research</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230901</creationdate><title>Investigating the Anti-Aging Effects of Caviar Oil on Human Skin</title><author>LE, LINH THI THUY ; KIM, BAEK-KYU ; CHIEN, PHAM NGOC ; CHOI, KEON-WOO ; KIM, HONG-BIN ; HWANG, UI-JAE ; HAN, HYO SUN ; HEO, CHAN-YEONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-dc7854b050a08c8d1ae9722317079426ea29140f72136016acba5718eb711fdc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LE, LINH THI THUY</creatorcontrib><creatorcontrib>KIM, BAEK-KYU</creatorcontrib><creatorcontrib>CHIEN, PHAM NGOC</creatorcontrib><creatorcontrib>CHOI, KEON-WOO</creatorcontrib><creatorcontrib>KIM, HONG-BIN</creatorcontrib><creatorcontrib>HWANG, UI-JAE</creatorcontrib><creatorcontrib>HAN, HYO SUN</creatorcontrib><creatorcontrib>HEO, CHAN-YEONG</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LE, LINH THI THUY</au><au>KIM, BAEK-KYU</au><au>CHIEN, PHAM NGOC</au><au>CHOI, KEON-WOO</au><au>KIM, HONG-BIN</au><au>HWANG, UI-JAE</au><au>HAN, HYO SUN</au><au>HEO, CHAN-YEONG</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Investigating the Anti-Aging Effects of Caviar Oil on Human Skin</atitle><jtitle>In vivo (Athens)</jtitle><date>2023-09-01</date><risdate>2023</risdate><volume>37</volume><issue>5</issue><spage>2078</spage><epage>2091</epage><pages>2078-2091</pages><issn>0258-851X</issn><issn>1791-7549</issn><eissn>1791-7549</eissn><abstract>As the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.BACKGROUND/AIMAs the largest organ of the human body, the skin serves as a critical barrier against environmental damage. However, many factors, such as genetics, sun exposure, and lifestyle choices can lead to skin damage creating wrinkles, sagging, and loss of elasticity. The use of skincare products containing natural ingredients has become increasingly popular as a way to combat the signs of aging. Caviar oil is one such ingredient that has gained attention due to its rich composition of fatty acids, vitamins, and minerals. The objective of this study was to investigate the potential anti-aging effects of caviar oil and to develop a product, Cavi Balm, which could potentially reduce wrinkles and skin sagging.An in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.MATERIALS AND METHODSAn in vitro model using the 3T3-L1 cell line was employed to assess the effect of caviar oil on adipocyte differentiation. An ex vivo study using human skin tissue was conducted to investigate the impact of caviar oil on collagen and elastin formation and the expression of matrix metalloproteinase-1,2,9 (MMP-1, MMP-2, MMP-9). Furthermore, 102 participants were enrolled in five clinical studies to evaluate the anti-aging efficacy of our product, "Cavi Balm", in facial and neck wrinkles, facial and eye area lifting, and various skin parameters, such as skin moisture, skin elasticity, skin density, skin tightening relief, skin clarity, and skin turnover.In vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.RESULTSIn vitro, caviar oil enhanced adipocyte differentiation, and increased lipid accumulation inside the cells. The ex vivo analysis revealed that caviar oil reduced the expression levels of MMP-1, MMP-2, and MMP-9, and increased the formation of elastin and collagen I, III. Moreover, in the clinical study, Cavi Balm improved skin parameters after one-time use, with more significant effects observed after four weeks of usage.Caviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.CONCLUSIONCaviar oil has a substantial impact on mitigating skin aging and holds potential for application in anti-aging products.</abstract><pub>International Institute of Anticancer Research</pub><pmid>37652485</pmid><doi>10.21873/invivo.13305</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record>
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title Investigating the Anti-Aging Effects of Caviar Oil on Human Skin
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