Emery-Dreifuss muscular dystrophy: localisation to Xq27.3----qter confirmed by linkage to the factor VIII gene

Two families with Emery-Dreifuss muscular dystrophy (EMD) have been studied with DNA markers mapping to Xq27.3---qter. No recombination was observed in 11 phase known meioses informative for the factor VIII gene (F8C) and eight phase known meioses informative for DXS15 (DX13), giving maximum lod sco...

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Veröffentlicht in:	Journal of medical genetics 1986-12, Vol.23 (6), p.587-590
Hauptverfasser:	Yates, J R, Affara, N A, Jamieson, D M, Ferguson-Smith, M A, Hausmanowa-Petrusewicz, I, Zaremba, J, Borkowska, J, Johnston, A W, Kelly, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Mapping Diseases of striated muscles. Neuromuscular diseases Factor VIII - genetics Genetic Linkage Humans Male Medical sciences Muscular Dystrophies - genetics Neurology Pedigree Polymorphism, Restriction Fragment Length Recombination, Genetic Syndrome X Chromosome
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