Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2‑(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation‑2 (ST2) Inhibitors

Hematopoietic cell transplantation (HCT) is a proven and potentially curable therapy for hematological malignancies and inherited hematological disease. The main risk of HCT is the development of graft versus host disease (GVHD) acquired in up to 50% of patients. Upregulation of soluble ST2 (sST2) i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS pharmacology & translational science 2023-09, Vol.6 (9), p.1275-1287
Hauptverfasser:	Yuan, Xinrui, Jiang, Hua, Fu, Denggang, Rech, Jason C., Robida, Aaron, Rajanayake, Krishani, Yuan, Hebao, He, Miao, Wen, Bo, Sun, Duxin, Liu, Chen, Chinnaswamy, Krishnapriya, Stuckey, Jeanne A., Paczesny, Sophie, Yang, Chao-Yie
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!