MAGED2 Depletion Promotes Stress-Induced Autophagy by Impairing the cAMP/PKA Pathway

Melanoma-associated antigen D2 (MAGED2) plays an essential role in activating the cAMP/PKA pathway under hypoxic conditions, which is crucial for stimulating renal salt reabsorption and thus explaining the transient variant of Bartter’s syndrome. The cAMP/PKA pathway is also known to regulate autoph...

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Veröffentlicht in:	International journal of molecular sciences 2023-09, Vol.24 (17), p.13433
Hauptverfasser:	Nasrah, Sadiq, Radi, Aline, Daberkow, Johanna K., Hummler, Helmut, Weber, Stefanie, Seaayfan, Elie, Kömhoff, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Cell cycle Cobalt Endoplasmic reticulum Hypoxia Kidneys Melanoma Mutation Oxidative stress Proteins
Online-Zugang:	Volltext
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