Multi-omics Characterization of Response to PD-1 Inhibitors in Advanced Melanoma

Immunotherapy improves the survival of patients with advanced melanoma, 40% of whom become long-term responders. However, not all patients respond to immunotherapy. Further knowledge of the processes involved in the response and resistance to immunotherapy is still needed. In this study, clinical pa...

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Veröffentlicht in:	Cancers 2023-09, Vol.15 (17), p.4407
Hauptverfasser:	Trilla-Fuertes, Lucía, Gámez-Pozo, Angelo, Prado-Vázquez, Guillermo, López-Vacas, Rocío, Soriano, Virtudes, Garicano, Fernando, Lecumberri, M. José, Rodríguez de la Borbolla, María, Majem, Margarita, Pérez-Ruiz, Elisabeth, González-Cao, María, Oramas, Juana, Magdaleno, Alejandra, Fra, Joaquín, Martín-Carnicero, Alfonso, Corral, Mónica, Puértolas, Teresa, Ramos-Ruiz, Ricardo, Dittmann, Antje, Nanni, Paolo, Fresno Vara, Juan Ángel, Espinosa, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen presentation Cancer Care and treatment Drug therapy Endoplasmic reticulum Genes Genomics Immunotherapy Inflammation Ions Mass spectrometry Medical prognosis Melanoma Normal distribution Paraffin Patients PD-1 protein Peptides Proteins Proteomics Scientific imaging Survival Transcriptomics
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