Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing

Abstract Hel308 helicases promote genome stability in archaea and are conserved in metazoans, where they are known as HELQ. Their helicase mechanism is well characterised, but it is unclear how they specifically contribute to genome stability in archaea. We show here that a highly conserved motif of...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2023-09, Vol.51 (16), p.8563-8574
Hauptverfasser:	Lever, Rebecca J, Simmons, Emily, Gamble-Milner, Rebecca, Buckley, Ryan J, Harrison, Catherine, Parkes, Ashley J, Mitchell, Laura, Gausden, Jacob A, Škulj, Sanja, Bertoša, Branimir, Bolt, Edward L, Allers, Thorsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Genome Integrity, Repair and
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!