NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells

Abstract NAT10-catalyzed N4-acetylcytidine (ac4C) has emerged as a vital post-transcriptional modulator on the coding transcriptome by promoting mRNA stability. However, its role in mammalian development remains unclear. Here, we found that NAT10 expression positively correlates with pluripotency in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2023-09, Vol.51 (16), p.8514-8531
Hauptverfasser:	Liu, Rucong, Wubulikasimu, Zibaguli, Cai, Runze, Meng, Fanyi, Cui, Qinghua, Zhou, Yuan, Li, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene regulation, Chromatin and Epigenetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!