Exploring olfactory receptor family 7 subfamily C member 1 as a novel oral cancer stem cell target for immunotherapy

The mortality rate of oral cancer has not improved over the past three decades despite remarkable advances in cancer therapies. Oral cancers contain a subpopulation of cancer stem cells (CSCs) that share characteristics associated with normal stem cells, including self‐renewal and multi‐differentiat...

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Veröffentlicht in:	Cancer science 2023-09, Vol.114 (9), p.3496-3508
Hauptverfasser:	Miyamoto, Sho, Hirohashi, Yoshihiko, Morita, Rena, Miyazaki, Akihiro, Ogi, Kazuhiro, Kanaseki, Takayuki, Ide, Kentaro, Shirakawa, Jumpei, Tsukahara, Tomohide, Murai, Aiko, Sasaya, Takashi, Koike, Kazushige, Kina, Shinichiro, Kawano, Toshihiro, Goto, Takahiro, Ntege, Edward Hosea, Shimizu, Yusuke, Torigoe, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Breast cancer cancer immunotherapy cancer stem cell Cancer therapies CD8 antigen Cell differentiation Cell self-renewal Colon Colon cancer Cytotoxicity Dehydrogenases Deoxyribonucleic acid DNA Drug resistance Growth factors Head & neck cancer Histocompatibility antigen HLA Immunotherapy Kinases Lymphocytes T Major histocompatibility complex Medical prognosis Medical research Metastases Odorant receptors OR7C1 Oral cancer Oral carcinoma Oral squamous cell carcinoma Original ORIGINAL ARTICLES peptide vaccine Polymerase chain reaction Radiation therapy Stem cells Tumor cell lines Tumors
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