A Randomized Controlled Pilot Study of Just4Us, a Counseling and Navigation Intervention to Promote Oral HIV Prophylaxis Uptake Among PrEP-Eligible Cisgender Women
HIV pre-exposure prophylaxis (PrEP) uptake among cisgender women in the United States is low. Just4Us, a theory-based counseling and navigation intervention, was evaluated in a pilot randomized controlled trial among PrEP-eligible women (n = 83). The comparison arm was a brief information session. W...
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| Veröffentlicht in: | AIDS and behavior 2023-09, Vol.27 (9), p.2944-2958 |
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| creator | Teitelman, Anne M. Tieu, Hong-Van Chittamuru, Deepti Shaw, Pamela A. Nandi, Vijay Davis, Annet Lipsky, Rachele K. Darlington, Caroline K. Fiore, Danielle Koblin, Beryl A. |
| description | HIV pre-exposure prophylaxis (PrEP) uptake among cisgender women in the United States is low. Just4Us, a theory-based counseling and navigation intervention, was evaluated in a pilot randomized controlled trial among PrEP-eligible women (n = 83). The comparison arm was a brief information session. Women completed surveys at baseline, post-intervention, and at three months. In this sample, 79% were Black, and 26% were Latina. This report presents results on preliminary efficacy. At 3 months follow-up, 45% made an appointment to see a provider about PrEP; only 13% received a PrEP prescription. There were no differences in PrEP initiation by study arm (9% Info vs. 11% Just4Us). PrEP knowledge was significantly higher in the Just4Us group at post-intervention. Analysis revealed high PrEP interest with many personal and structural barriers along the PrEP continuum. Just4Us is a promising PrEP uptake intervention for cisgender women. Further research is needed to tailor intervention strategies to multilevel barriers.
Clinicaltrials.gov registration
NCT03699722: A Women-Focused PrEP Intervention (Just4Us). |
| doi_str_mv | 10.1007/s10461-023-04017-z |
| format | Article |
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Clinicaltrials.gov registration
NCT03699722: A Women-Focused PrEP Intervention (Just4Us).</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-023-04017-z</identifier><identifier>PMID: 36869921</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Anti-HIV Agents - therapeutic use ; Cisgender ; Cognition ; Counseling ; Disease prevention ; Female ; Health Psychology ; Hispanic Americans ; HIV ; HIV Infections - prevention & control ; Human immunodeficiency virus ; Humans ; Infectious Diseases ; Intervention ; Latin American cultural groups ; Medicine ; Medicine & Public Health ; NCT ; NCT03699722 ; Original Paper ; Pilot Projects ; Pre-Exposure Prophylaxis - methods ; Prophylaxis ; Public Health ; United States ; Women</subject><ispartof>AIDS and behavior, 2023-09, Vol.27 (9), p.2944-2958</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-77a3a4384186bb48e3cd95ae6a1faa4e5607f98ba3f7d29797451d3b7ce5a12e3</citedby><cites>FETCH-LOGICAL-c475t-77a3a4384186bb48e3cd95ae6a1faa4e5607f98ba3f7d29797451d3b7ce5a12e3</cites><orcidid>0000-0001-6292-5648</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10461-023-04017-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10461-023-04017-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27344,27924,27925,33774,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36869921$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Teitelman, Anne M.</creatorcontrib><creatorcontrib>Tieu, Hong-Van</creatorcontrib><creatorcontrib>Chittamuru, Deepti</creatorcontrib><creatorcontrib>Shaw, Pamela A.</creatorcontrib><creatorcontrib>Nandi, Vijay</creatorcontrib><creatorcontrib>Davis, Annet</creatorcontrib><creatorcontrib>Lipsky, Rachele K.</creatorcontrib><creatorcontrib>Darlington, Caroline K.</creatorcontrib><creatorcontrib>Fiore, Danielle</creatorcontrib><creatorcontrib>Koblin, Beryl A.</creatorcontrib><title>A Randomized Controlled Pilot Study of Just4Us, a Counseling and Navigation Intervention to Promote Oral HIV Prophylaxis Uptake Among PrEP-Eligible Cisgender Women</title><title>AIDS and behavior</title><addtitle>AIDS Behav</addtitle><addtitle>AIDS Behav</addtitle><description>HIV pre-exposure prophylaxis (PrEP) uptake among cisgender women in the United States is low. Just4Us, a theory-based counseling and navigation intervention, was evaluated in a pilot randomized controlled trial among PrEP-eligible women (n = 83). The comparison arm was a brief information session. Women completed surveys at baseline, post-intervention, and at three months. In this sample, 79% were Black, and 26% were Latina. This report presents results on preliminary efficacy. At 3 months follow-up, 45% made an appointment to see a provider about PrEP; only 13% received a PrEP prescription. There were no differences in PrEP initiation by study arm (9% Info vs. 11% Just4Us). PrEP knowledge was significantly higher in the Just4Us group at post-intervention. Analysis revealed high PrEP interest with many personal and structural barriers along the PrEP continuum. Just4Us is a promising PrEP uptake intervention for cisgender women. Further research is needed to tailor intervention strategies to multilevel barriers.
Clinicaltrials.gov registration
NCT03699722: A Women-Focused PrEP Intervention (Just4Us).</description><subject>Anti-HIV Agents - therapeutic use</subject><subject>Cisgender</subject><subject>Cognition</subject><subject>Counseling</subject><subject>Disease prevention</subject><subject>Female</subject><subject>Health Psychology</subject><subject>Hispanic Americans</subject><subject>HIV</subject><subject>HIV Infections - prevention & control</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Intervention</subject><subject>Latin American cultural groups</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>NCT</subject><subject>NCT03699722</subject><subject>Original Paper</subject><subject>Pilot Projects</subject><subject>Pre-Exposure Prophylaxis - methods</subject><subject>Prophylaxis</subject><subject>Public Health</subject><subject>United States</subject><subject>Women</subject><issn>1090-7165</issn><issn>1573-3254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>BHHNA</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ks9u1DAQxiMEoqXwAhyQJS4cCNixE9sntFotdFFFV8DC0XKSSeri2Fs7WbH7OrwobreUPwdOHnt-83lG82XZU4JfEYz560gwq0iOC5pjhgnP9_eyY1JymtOiZPdTjCXOOanKo-xRjJcYY1lx-TA7opWopCzIcfZjhj5q1_rB7KFFc-_G4K1N4cpYP6JP49TukO_Q-ymObB1fIp2gyUWwxvUoVaIPemt6PRrv0NKNELbgbi6jR6vgBz8COg_aotPll-uHzcXO6u8movVm1N8AzQafhFZhscoX1vSmtoDmJvbgWgjoqx_APc4edNpGeHJ7nmTrt4vP89P87Pzdcj47yxvGyzHnXFPNqGBEVHXNBNCmlaWGSpNOawZlhXknRa1px9tCcslZSVpa8wZKTQqgJ9mbg-5mqgdomzRIalxtghl02Cmvjfo748yF6v1WpT3wkgmRFF7cKgR_NUEc1WBiA9ZqB36KquCCMomlqBL6_B_00k_BpflUIRhlXIiiTFRxoJrgYwzQ3XVDsLo2gTqYQCUTqBsTqH0qevbnHHclv7aeAHoAYkq5HsLvv_8j-xOv38As</recordid><startdate>20230901</startdate><enddate>20230901</enddate><creator>Teitelman, Anne M.</creator><creator>Tieu, Hong-Van</creator><creator>Chittamuru, Deepti</creator><creator>Shaw, Pamela A.</creator><creator>Nandi, Vijay</creator><creator>Davis, Annet</creator><creator>Lipsky, Rachele K.</creator><creator>Darlington, Caroline K.</creator><creator>Fiore, Danielle</creator><creator>Koblin, Beryl A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7T2</scope><scope>7U3</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AM</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGRYB</scope><scope>BHHNA</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HEHIP</scope><scope>K7.</scope><scope>K9.</scope><scope>KB0</scope><scope>M0O</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6292-5648</orcidid></search><sort><creationdate>20230901</creationdate><title>A Randomized Controlled Pilot Study of Just4Us, a Counseling and Navigation Intervention to Promote Oral HIV Prophylaxis Uptake Among PrEP-Eligible Cisgender Women</title><author>Teitelman, Anne M. ; Tieu, Hong-Van ; Chittamuru, Deepti ; Shaw, Pamela A. ; Nandi, Vijay ; Davis, Annet ; Lipsky, Rachele K. ; Darlington, Caroline K. ; Fiore, Danielle ; Koblin, Beryl A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-77a3a4384186bb48e3cd95ae6a1faa4e5607f98ba3f7d29797451d3b7ce5a12e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anti-HIV Agents - therapeutic use</topic><topic>Cisgender</topic><topic>Cognition</topic><topic>Counseling</topic><topic>Disease prevention</topic><topic>Female</topic><topic>Health Psychology</topic><topic>Hispanic Americans</topic><topic>HIV</topic><topic>HIV Infections - prevention & control</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Infectious Diseases</topic><topic>Intervention</topic><topic>Latin American cultural groups</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>NCT</topic><topic>NCT03699722</topic><topic>Original Paper</topic><topic>Pilot Projects</topic><topic>Pre-Exposure Prophylaxis - methods</topic><topic>Prophylaxis</topic><topic>Public Health</topic><topic>United States</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Teitelman, Anne M.</creatorcontrib><creatorcontrib>Tieu, Hong-Van</creatorcontrib><creatorcontrib>Chittamuru, Deepti</creatorcontrib><creatorcontrib>Shaw, Pamela A.</creatorcontrib><creatorcontrib>Nandi, Vijay</creatorcontrib><creatorcontrib>Davis, Annet</creatorcontrib><creatorcontrib>Lipsky, Rachele K.</creatorcontrib><creatorcontrib>Darlington, Caroline K.</creatorcontrib><creatorcontrib>Fiore, Danielle</creatorcontrib><creatorcontrib>Koblin, Beryl A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Social Services Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Criminal Justice Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Criminology Collection</collection><collection>Sociological Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Sociology Collection</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Criminal Justice Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Sociology Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>AIDS and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Teitelman, Anne M.</au><au>Tieu, Hong-Van</au><au>Chittamuru, Deepti</au><au>Shaw, Pamela A.</au><au>Nandi, Vijay</au><au>Davis, Annet</au><au>Lipsky, Rachele K.</au><au>Darlington, Caroline K.</au><au>Fiore, Danielle</au><au>Koblin, Beryl A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Randomized Controlled Pilot Study of Just4Us, a Counseling and Navigation Intervention to Promote Oral HIV Prophylaxis Uptake Among PrEP-Eligible Cisgender Women</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2023-09-01</date><risdate>2023</risdate><volume>27</volume><issue>9</issue><spage>2944</spage><epage>2958</epage><pages>2944-2958</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><abstract>HIV pre-exposure prophylaxis (PrEP) uptake among cisgender women in the United States is low. Just4Us, a theory-based counseling and navigation intervention, was evaluated in a pilot randomized controlled trial among PrEP-eligible women (n = 83). The comparison arm was a brief information session. Women completed surveys at baseline, post-intervention, and at three months. In this sample, 79% were Black, and 26% were Latina. This report presents results on preliminary efficacy. At 3 months follow-up, 45% made an appointment to see a provider about PrEP; only 13% received a PrEP prescription. There were no differences in PrEP initiation by study arm (9% Info vs. 11% Just4Us). PrEP knowledge was significantly higher in the Just4Us group at post-intervention. Analysis revealed high PrEP interest with many personal and structural barriers along the PrEP continuum. Just4Us is a promising PrEP uptake intervention for cisgender women. Further research is needed to tailor intervention strategies to multilevel barriers.
Clinicaltrials.gov registration
NCT03699722: A Women-Focused PrEP Intervention (Just4Us).</abstract><cop>New York</cop><pub>Springer US</pub><pmid>36869921</pmid><doi>10.1007/s10461-023-04017-z</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0001-6292-5648</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | AIDS and behavior, 2023-09, Vol.27 (9), p.2944-2958 |
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| source | MEDLINE; Sociological Abstracts; SpringerLink Journals - AutoHoldings |
| subjects | Anti-HIV Agents - therapeutic use Cisgender Cognition Counseling Disease prevention Female Health Psychology Hispanic Americans HIV HIV Infections - prevention & control Human immunodeficiency virus Humans Infectious Diseases Intervention Latin American cultural groups Medicine Medicine & Public Health NCT NCT03699722 Original Paper Pilot Projects Pre-Exposure Prophylaxis - methods Prophylaxis Public Health United States Women |
| title | A Randomized Controlled Pilot Study of Just4Us, a Counseling and Navigation Intervention to Promote Oral HIV Prophylaxis Uptake Among PrEP-Eligible Cisgender Women |
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