Aurantio-obtusin ameliorates obesity by activating PPARα-dependent mitochondrial thermogenesis in brown adipose tissues

Obesity contributes to the progression of various chronic diseases, and shortens life expectancy. With abundant mitochondria, brown adipose tissue (BAT) dissipates energy through heat to limit weight gain and metabolic dysfunction in obesity. Our previous studies have shown that aurantio-obtusin (AO...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta pharmacologica Sinica 2023-09, Vol.44 (9), p.1826-1840
Hauptverfasser:	Li, Yi-jie, Wu, Rui-yu, Liu, Run-ping, Wu, Kai-yi, Ding, Ming-ning, Sun, Rong, Gu, Yi-qing, Zhou, Fei, Wu, Jian-zhi, Zheng, Qi, Duan, Shu-ni, Li, Rong-rong, Zhang, Yin-hao, Li, Fang-hong, Li, Xiaojiaoyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissue (brown) Adipose Tissue, Brown - metabolism Adipose Tissue, White - metabolism Animals Biomedical and Life Sciences Biomedicine Body fat Body weight gain Comorbidity Diet Energy expenditure Energy Metabolism Immunology Internal Medicine Life span Lipid metabolism Lipids Liver diseases Low temperature Medical Microbiology Metabolism Mice Mice, Inbred C57BL Mice, Obese Mitochondria Mitochondria - metabolism Obesity Obesity - drug therapy Obesity - metabolism Oleic acid Palmitic acid Pharmacology/Toxicology PPAR alpha - metabolism Thermogenesis Vaccine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!