Quinpirole, but not muscimol, infused into the nucleus accumbens disrupts prepulse inhibition of the acoustic startle in rhesus macaques

Sensorimotor gating is the ability to suppress motor responses to irrelevant sensory inputs. This response is disrupted in a range of neuropsychiatric disorders. Prepulse inhibition (PPI) of the acoustic startle response (ASR) is a form of sensorimotor gating in which a low-intensity prepulse immedi...

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Veröffentlicht in:	Neuropharmacology 2023-09, Vol.235, p.109563-109563, Article 109563
Hauptverfasser:	Waguespack, Hannah F., Maior, Rafael S., Campos-Rodriguez, Carolina, Jacobs, Jessica T., Malkova, Ludise, Forcelli, Patrick A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation - methods Acoustics Animals Dopamine Dopamine Agonists - pharmacology GABA Macaca mulatta Macaque Muscimol - pharmacology Nucleus Accumbens Prepulse Inhibition Quinpirole - pharmacology Reflex, Startle Sensorimotor gating
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