Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina
In the United States [1] between 7-10% of all liver transplants constitute retransplants, while in our country this group represents 5-7% [5]. Since the beginning of LT, liverretransplantation (re-LT) has been recognized as a challenge, not only for its technical complexity but also for all the aspe...
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| Veröffentlicht in: | International journal of organ transplantation medicine 2022-01, Vol.13 (2), p.30-35 |
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| creator | Bruballa, R Thomas, D Sanchez de Santibañes, E Ciardullo, M Mattera, J Pekolj, J de Santibañes, M Ardiles, V |
| description | In the United States [1] between 7-10% of all liver transplants constitute retransplants, while in our country this group represents 5-7% [5]. Since the beginning of LT, liverretransplantation (re-LT) has been recognized as a challenge, not only for its technical complexity but also for all the aspects involved in the evolution of the patient. According to the available evidence, the prognosis for both graft and receptor is poorer for re-LT. Statistical Analysis For the descriptive analysis, continuous variables were expressed as mean and standard deviation or median and interquartile range according to the observed distribution. The assumption of proportionality of the risks and the interaction of the variables with time were tested graphically (graph of the risk functions and their logarithms, comparison of predicted and observed values) and statistically (Schoenfeld test), and the ability to discriminate of the crude and adjusted model using Harrell's C index. |
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Since the beginning of LT, liverretransplantation (re-LT) has been recognized as a challenge, not only for its technical complexity but also for all the aspects involved in the evolution of the patient. According to the available evidence, the prognosis for both graft and receptor is poorer for re-LT. Statistical Analysis For the descriptive analysis, continuous variables were expressed as mean and standard deviation or median and interquartile range according to the observed distribution. The assumption of proportionality of the risks and the interaction of the variables with time were tested graphically (graph of the risk functions and their logarithms, comparison of predicted and observed values) and statistically (Schoenfeld test), and the ability to discriminate of the crude and adjusted model using Harrell's C index.</description><identifier>ISSN: 2008-6482</identifier><identifier>EISSN: 2008-6490</identifier><language>eng</language><publisher>Shiraz: Shiraz University of Medical Sciences</publisher><subject>Adults ; Confidence intervals ; Hepatitis ; Liver diseases ; Liver transplants ; Medical prognosis ; Original ; Patients ; Population ; Statistical analysis ; Surgical techniques</subject><ispartof>International journal of organ transplantation medicine, 2022-01, Vol.13 (2), p.30-35</ispartof><rights>Copyright Shiraz University of Medical Sciences 2022</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460530/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460530/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53789,53791</link.rule.ids></links><search><creatorcontrib>Bruballa, R</creatorcontrib><creatorcontrib>Thomas, D Sanchez</creatorcontrib><creatorcontrib>de Santibañes, E</creatorcontrib><creatorcontrib>Ciardullo, M</creatorcontrib><creatorcontrib>Mattera, J</creatorcontrib><creatorcontrib>Pekolj, J</creatorcontrib><creatorcontrib>de Santibañes, M</creatorcontrib><creatorcontrib>Ardiles, V</creatorcontrib><title>Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina</title><title>International journal of organ transplantation medicine</title><description>In the United States [1] between 7-10% of all liver transplants constitute retransplants, while in our country this group represents 5-7% [5]. Since the beginning of LT, liverretransplantation (re-LT) has been recognized as a challenge, not only for its technical complexity but also for all the aspects involved in the evolution of the patient. According to the available evidence, the prognosis for both graft and receptor is poorer for re-LT. Statistical Analysis For the descriptive analysis, continuous variables were expressed as mean and standard deviation or median and interquartile range according to the observed distribution. The assumption of proportionality of the risks and the interaction of the variables with time were tested graphically (graph of the risk functions and their logarithms, comparison of predicted and observed values) and statistically (Schoenfeld test), and the ability to discriminate of the crude and adjusted model using Harrell's C index.</description><subject>Adults</subject><subject>Confidence intervals</subject><subject>Hepatitis</subject><subject>Liver diseases</subject><subject>Liver transplants</subject><subject>Medical prognosis</subject><subject>Original</subject><subject>Patients</subject><subject>Population</subject><subject>Statistical analysis</subject><subject>Surgical techniques</subject><issn>2008-6482</issn><issn>2008-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkE9LAzEQxRdRsNR-h4AXLwvZZDebeJFSqhYKBf-clzSZrSnbZE2yxR787qZaBJ3LPGYevwfvLBsRjHnOSoHPfzUnl9kkhC1OQwVjhI6yz6XZg0dPkEcvbeg7aaOMxllkLJrqoYvhFi2sNur7GpC0Gq2GqNwOAppa2R2CCci1SCJC8wNIj-YfPXgDVsERItGzsZsO0AxsTFFHrt8kbay8yi5a2QWYnPY4e72fv8we8-XqYTGbLvOe1CTmQrfApShZjQkmQlEFhKyF4IRUpZYFZ21LgNUUuGZaY1EwyZiqS6UpLgpMx9ndD7cf1jvQKqV72TW9NzvpD42Tpvn7seat2bh9U-CS4YoeCTcngnfvA4TY7ExQ0KW-wA2hIbzigvOKlcl6_c-6dYNPTSVXXeKqEkVV0C_0g4DO</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Bruballa, R</creator><creator>Thomas, D Sanchez</creator><creator>de Santibañes, E</creator><creator>Ciardullo, M</creator><creator>Mattera, J</creator><creator>Pekolj, J</creator><creator>de Santibañes, M</creator><creator>Ardiles, V</creator><general>Shiraz University of Medical Sciences</general><general>Avicenna Organ Transplantation Institute</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220101</creationdate><title>Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina</title><author>Bruballa, R ; Thomas, D Sanchez ; de Santibañes, E ; Ciardullo, M ; Mattera, J ; Pekolj, J ; de Santibañes, M ; Ardiles, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p272t-9dfe8a946702029c3ce22b9982254da186ff2e673e8d6dd0916a66c74cd301103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adults</topic><topic>Confidence intervals</topic><topic>Hepatitis</topic><topic>Liver diseases</topic><topic>Liver transplants</topic><topic>Medical prognosis</topic><topic>Original</topic><topic>Patients</topic><topic>Population</topic><topic>Statistical analysis</topic><topic>Surgical techniques</topic><toplevel>online_resources</toplevel><creatorcontrib>Bruballa, R</creatorcontrib><creatorcontrib>Thomas, D Sanchez</creatorcontrib><creatorcontrib>de Santibañes, E</creatorcontrib><creatorcontrib>Ciardullo, M</creatorcontrib><creatorcontrib>Mattera, J</creatorcontrib><creatorcontrib>Pekolj, J</creatorcontrib><creatorcontrib>de Santibañes, M</creatorcontrib><creatorcontrib>Ardiles, V</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of organ transplantation medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bruballa, R</au><au>Thomas, D Sanchez</au><au>de Santibañes, E</au><au>Ciardullo, M</au><au>Mattera, J</au><au>Pekolj, J</au><au>de Santibañes, M</au><au>Ardiles, V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina</atitle><jtitle>International journal of organ transplantation medicine</jtitle><date>2022-01-01</date><risdate>2022</risdate><volume>13</volume><issue>2</issue><spage>30</spage><epage>35</epage><pages>30-35</pages><issn>2008-6482</issn><eissn>2008-6490</eissn><abstract>In the United States [1] between 7-10% of all liver transplants constitute retransplants, while in our country this group represents 5-7% [5]. Since the beginning of LT, liverretransplantation (re-LT) has been recognized as a challenge, not only for its technical complexity but also for all the aspects involved in the evolution of the patient. According to the available evidence, the prognosis for both graft and receptor is poorer for re-LT. Statistical Analysis For the descriptive analysis, continuous variables were expressed as mean and standard deviation or median and interquartile range according to the observed distribution. The assumption of proportionality of the risks and the interaction of the variables with time were tested graphically (graph of the risk functions and their logarithms, comparison of predicted and observed values) and statistically (Schoenfeld test), and the ability to discriminate of the crude and adjusted model using Harrell's C index.</abstract><cop>Shiraz</cop><pub>Shiraz University of Medical Sciences</pub><tpages>6</tpages></addata></record> |
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| ispartof | International journal of organ transplantation medicine, 2022-01, Vol.13 (2), p.30-35 |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adults Confidence intervals Hepatitis Liver diseases Liver transplants Medical prognosis Original Patients Population Statistical analysis Surgical techniques |
| title | Liver Re-transplantation in Adults: Indications and Outcomes Analysis of a 23-year Experience in a Single Center in Argentina |
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