Preemptive TPMT Genotyping and Adherence to Genotype-Based Therapeutic Recommendations Reduces the Healthcare Cost in Patients Receiving Azathioprine or 6-Mercaptopurine for Autoimmune Diseases

A cost analysis of thiopurine treatment was carried out in 257 patients, with 153 preemptively genotyped for TPMT and 104 retrospectively genotyped in a Spanish setting. The healthcare cost was significantly higher in patients retrospectively genotyped compared to those who were preemptively genotyp...

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Veröffentlicht in:	Journal of personalized medicine 2023-07, Vol.13 (8), p.1208
Hauptverfasser:	Valdez-Acosta, Sarahí, Zubiaur, Pablo, Casado, Miguel Angel, Novalbos, Jesús, Casajús, Ana, Campodónico, Diana, Oyagüez, Itziar, Abad-Santos, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Mercaptopurine Autoimmune diseases Azathioprine Cell division Consortia Cost analysis Disease Drug dosages Genotype & phenotype Genotypes Genotyping Health care Hospitals Medical diagnosis Metabolites Myelosuppression Patients Phenotypes Precision medicine Statistical analysis Toxicity Variables
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