Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis
Diet is the primary exposure pathway for phthalates, but relative contributions of other exposure sources are not well characterized. This study quantifies the relative contribution of indoor residential dust phthalate and phthalate alternative concentrations to total internal dose estimated from th...
Gespeichert in:
| Veröffentlicht in: | International journal of environmental research and public health 2023-08, Vol.20 (16), p.6589 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 16 |
| container_start_page | 6589 |
| container_title | International journal of environmental research and public health |
| container_volume | 20 |
| creator | Milton, Sashoy G Tejiram, Rachel A Joglekar, Rashmi Hoffman, Kate |
| description | Diet is the primary exposure pathway for phthalates, but relative contributions of other exposure sources are not well characterized. This study quantifies the relative contribution of indoor residential dust phthalate and phthalate alternative concentrations to total internal dose estimated from the National Health and Nutrition Examination Survey (NHANES) urinary metabolite concentrations. Specifically, median phthalate and phthalate alternative concentrations measured in residential dust were determined by updating a pre-existing systematic review and meta-analysis published in 2015 and the attributable internal dose was estimated using intake and reverse dosimetry models. Employing a predetermined search strategy, 12 studies published between January 2000 and April 2022 from Web of Science and PubMed measuring phthalates and phthalate alternatives in residential dust were identified. From the data extracted, it was estimated that dust contributed more significantly to the internal dose of low-molecular weight chemicals such as DEP and BBP when compared to high-molecular weight chemicals such as DEHTP. Additionally, findings showed that the chemical profile of residential dust is changing temporally with more phthalate alternatives being detected in the indoor environment. Future studies should seek to characterize the contribution of dust to an overall phthalate and phthalate alternative intake for individuals who have higher than normal exposures. |
| doi_str_mv | 10.3390/ijerph20166589 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10454216</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2857844902</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3349-a24912e295b53e21cb9e71063a680eeab5b76edc0e92ef731ea66072345048dc3</originalsourceid><addsrcrecordid>eNpdkktv1DAQgC0EoqVw5YgsceGS4lce5oJWWyiVikCUPVtOMtt4lbVT21m0_EX-FE62VFtOHtvffPaMBqHXlJxzLsl7swE_dIzQosgr-QSdpoBkoiD06VF8gl6EsCGEV6KQz9EJLwvGaSlO0Z9lp71uInjz29hbHDvAS2ejN_UYjbPYrfGVbZ3z-AcE04KNRvf4exc73esIWNv2aLfok8nqaHaAL8YQJ1eTcryeZAFHl2wz0uMLFwAbOz-5usGXYMFPajeM_Yx_wAuLV0ObxC2-2YcI23TepI_sDPyaX_4KUWeLZNsHE16iZ2vdB3h1v56h1edPP5dfsutvl1fLxXXWcC5kppmQlAGTeZ1zYLSpJZSUFFwXFQHQdV6XBbQNAclgXXIKOvWxZFzkRFRtw8_Qx4N3GOttAuf6ejV4s9V-r5w26vGNNZ26dTtFicgFo0UyvLs3eHc3Qohqa0IDfa8tuDEoVuVlJYQkLKFv_0M3bpz6d6BIKVglEnV-oBrvQvCwfvgNJWoaFPV4UFLCm-MaHvB_k8H_AvF2vts</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2857074284</pqid></control><display><type>article</type><title>Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis</title><source>MEDLINE</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Milton, Sashoy G ; Tejiram, Rachel A ; Joglekar, Rashmi ; Hoffman, Kate</creator><creatorcontrib>Milton, Sashoy G ; Tejiram, Rachel A ; Joglekar, Rashmi ; Hoffman, Kate</creatorcontrib><description>Diet is the primary exposure pathway for phthalates, but relative contributions of other exposure sources are not well characterized. This study quantifies the relative contribution of indoor residential dust phthalate and phthalate alternative concentrations to total internal dose estimated from the National Health and Nutrition Examination Survey (NHANES) urinary metabolite concentrations. Specifically, median phthalate and phthalate alternative concentrations measured in residential dust were determined by updating a pre-existing systematic review and meta-analysis published in 2015 and the attributable internal dose was estimated using intake and reverse dosimetry models. Employing a predetermined search strategy, 12 studies published between January 2000 and April 2022 from Web of Science and PubMed measuring phthalates and phthalate alternatives in residential dust were identified. From the data extracted, it was estimated that dust contributed more significantly to the internal dose of low-molecular weight chemicals such as DEP and BBP when compared to high-molecular weight chemicals such as DEHTP. Additionally, findings showed that the chemical profile of residential dust is changing temporally with more phthalate alternatives being detected in the indoor environment. Future studies should seek to characterize the contribution of dust to an overall phthalate and phthalate alternative intake for individuals who have higher than normal exposures.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph20166589</identifier><identifier>PMID: 37623174</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Dust ; Estimates ; Humans ; Meta-analysis ; Molecular Weight ; Nutrition Surveys ; Phthalic Acids ; Population ; Software ; Systematic Review ; Thinness ; Toxicity</subject><ispartof>International journal of environmental research and public health, 2023-08, Vol.20 (16), p.6589</ispartof><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 by the authors. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3349-a24912e295b53e21cb9e71063a680eeab5b76edc0e92ef731ea66072345048dc3</citedby><cites>FETCH-LOGICAL-c3349-a24912e295b53e21cb9e71063a680eeab5b76edc0e92ef731ea66072345048dc3</cites><orcidid>0009-0000-5583-3294</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454216/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454216/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37623174$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Milton, Sashoy G</creatorcontrib><creatorcontrib>Tejiram, Rachel A</creatorcontrib><creatorcontrib>Joglekar, Rashmi</creatorcontrib><creatorcontrib>Hoffman, Kate</creatorcontrib><title>Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>Diet is the primary exposure pathway for phthalates, but relative contributions of other exposure sources are not well characterized. This study quantifies the relative contribution of indoor residential dust phthalate and phthalate alternative concentrations to total internal dose estimated from the National Health and Nutrition Examination Survey (NHANES) urinary metabolite concentrations. Specifically, median phthalate and phthalate alternative concentrations measured in residential dust were determined by updating a pre-existing systematic review and meta-analysis published in 2015 and the attributable internal dose was estimated using intake and reverse dosimetry models. Employing a predetermined search strategy, 12 studies published between January 2000 and April 2022 from Web of Science and PubMed measuring phthalates and phthalate alternatives in residential dust were identified. From the data extracted, it was estimated that dust contributed more significantly to the internal dose of low-molecular weight chemicals such as DEP and BBP when compared to high-molecular weight chemicals such as DEHTP. Additionally, findings showed that the chemical profile of residential dust is changing temporally with more phthalate alternatives being detected in the indoor environment. Future studies should seek to characterize the contribution of dust to an overall phthalate and phthalate alternative intake for individuals who have higher than normal exposures.</description><subject>Dust</subject><subject>Estimates</subject><subject>Humans</subject><subject>Meta-analysis</subject><subject>Molecular Weight</subject><subject>Nutrition Surveys</subject><subject>Phthalic Acids</subject><subject>Population</subject><subject>Software</subject><subject>Systematic Review</subject><subject>Thinness</subject><subject>Toxicity</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkktv1DAQgC0EoqVw5YgsceGS4lce5oJWWyiVikCUPVtOMtt4lbVT21m0_EX-FE62VFtOHtvffPaMBqHXlJxzLsl7swE_dIzQosgr-QSdpoBkoiD06VF8gl6EsCGEV6KQz9EJLwvGaSlO0Z9lp71uInjz29hbHDvAS2ejN_UYjbPYrfGVbZ3z-AcE04KNRvf4exc73esIWNv2aLfok8nqaHaAL8YQJ1eTcryeZAFHl2wz0uMLFwAbOz-5usGXYMFPajeM_Yx_wAuLV0ObxC2-2YcI23TepI_sDPyaX_4KUWeLZNsHE16iZ2vdB3h1v56h1edPP5dfsutvl1fLxXXWcC5kppmQlAGTeZ1zYLSpJZSUFFwXFQHQdV6XBbQNAclgXXIKOvWxZFzkRFRtw8_Qx4N3GOttAuf6ejV4s9V-r5w26vGNNZ26dTtFicgFo0UyvLs3eHc3Qohqa0IDfa8tuDEoVuVlJYQkLKFv_0M3bpz6d6BIKVglEnV-oBrvQvCwfvgNJWoaFPV4UFLCm-MaHvB_k8H_AvF2vts</recordid><startdate>20230817</startdate><enddate>20230817</enddate><creator>Milton, Sashoy G</creator><creator>Tejiram, Rachel A</creator><creator>Joglekar, Rashmi</creator><creator>Hoffman, Kate</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0009-0000-5583-3294</orcidid></search><sort><creationdate>20230817</creationdate><title>Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis</title><author>Milton, Sashoy G ; Tejiram, Rachel A ; Joglekar, Rashmi ; Hoffman, Kate</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3349-a24912e295b53e21cb9e71063a680eeab5b76edc0e92ef731ea66072345048dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Dust</topic><topic>Estimates</topic><topic>Humans</topic><topic>Meta-analysis</topic><topic>Molecular Weight</topic><topic>Nutrition Surveys</topic><topic>Phthalic Acids</topic><topic>Population</topic><topic>Software</topic><topic>Systematic Review</topic><topic>Thinness</topic><topic>Toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Milton, Sashoy G</creatorcontrib><creatorcontrib>Tejiram, Rachel A</creatorcontrib><creatorcontrib>Joglekar, Rashmi</creatorcontrib><creatorcontrib>Hoffman, Kate</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Milton, Sashoy G</au><au>Tejiram, Rachel A</au><au>Joglekar, Rashmi</au><au>Hoffman, Kate</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2023-08-17</date><risdate>2023</risdate><volume>20</volume><issue>16</issue><spage>6589</spage><pages>6589-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>Diet is the primary exposure pathway for phthalates, but relative contributions of other exposure sources are not well characterized. This study quantifies the relative contribution of indoor residential dust phthalate and phthalate alternative concentrations to total internal dose estimated from the National Health and Nutrition Examination Survey (NHANES) urinary metabolite concentrations. Specifically, median phthalate and phthalate alternative concentrations measured in residential dust were determined by updating a pre-existing systematic review and meta-analysis published in 2015 and the attributable internal dose was estimated using intake and reverse dosimetry models. Employing a predetermined search strategy, 12 studies published between January 2000 and April 2022 from Web of Science and PubMed measuring phthalates and phthalate alternatives in residential dust were identified. From the data extracted, it was estimated that dust contributed more significantly to the internal dose of low-molecular weight chemicals such as DEP and BBP when compared to high-molecular weight chemicals such as DEHTP. Additionally, findings showed that the chemical profile of residential dust is changing temporally with more phthalate alternatives being detected in the indoor environment. Future studies should seek to characterize the contribution of dust to an overall phthalate and phthalate alternative intake for individuals who have higher than normal exposures.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>37623174</pmid><doi>10.3390/ijerph20166589</doi><orcidid>https://orcid.org/0009-0000-5583-3294</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1660-4601 |
| ispartof | International journal of environmental research and public health, 2023-08, Vol.20 (16), p.6589 |
| issn | 1660-4601 1661-7827 1660-4601 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10454216 |
| source | MEDLINE; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Dust Estimates Humans Meta-analysis Molecular Weight Nutrition Surveys Phthalic Acids Population Software Systematic Review Thinness Toxicity |
| title | Characterizing the Contribution of Indoor Residential Phthalate and Phthalate Alternative Dust Concentrations to Internal Dose in the US General Population: An Updated Systematic Review and Meta-Analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T13%3A22%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Characterizing%20the%20Contribution%20of%20Indoor%20Residential%20Phthalate%20and%20Phthalate%20Alternative%20Dust%20Concentrations%20to%20Internal%20Dose%20in%20the%20US%20General%20Population:%20An%20Updated%20Systematic%20Review%20and%20Meta-Analysis&rft.jtitle=International%20journal%20of%20environmental%20research%20and%20public%20health&rft.au=Milton,%20Sashoy%20G&rft.date=2023-08-17&rft.volume=20&rft.issue=16&rft.spage=6589&rft.pages=6589-&rft.issn=1660-4601&rft.eissn=1660-4601&rft_id=info:doi/10.3390/ijerph20166589&rft_dat=%3Cproquest_pubme%3E2857844902%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2857074284&rft_id=info:pmid/37623174&rfr_iscdi=true |