Rapid Classification of Sarcomas Using Methylation Fingerprint: A Pilot Study

Sarcoma classification is challenging and can lead to treatment delays. Previous studies used DNA aberrations and machine-learning classifiers based on methylation profiles for diagnosis. We aimed to classify sarcomas by analyzing methylation signatures obtained from low-coverage whole-genome sequen...

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Veröffentlicht in:	Cancers 2023-08, Vol.15 (16), p.4168
Hauptverfasser:	Iluz, Aviel, Maoz, Myriam, Lavi, Nir, Charbit, Hanna, Or, Omer, Olshinka, Noam, Demma, Jonathan Abraham, Adileh, Mohammad, Wygoda, Marc, Blumenfeld, Philip, Gliner-Ron, Masha, Azraq, Yusef, Moss, Joshua, Peretz, Tamar, Eden, Amir, Zick, Aviad, Lavon, Iris
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrays Bar codes Bone cancer Brain cancer Chemotherapy Classification DNA methylation DNA sequencing Embedding Gene mutations Genomes Genomics Machine learning Methylation Nucleotide sequence Nucleotide sequencing Pathology Protein expression Proteins Radiation therapy Sarcoma Software Stochasticity Translocation Tumors Whole genome sequencing
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