BRAF Mutations in Melanoma: Biological Aspects, Therapeutic Implications, and Circulating Biomarkers

Melanoma is an aggressive form of skin cancer resulting from the malignant transformation of melanocytes. Recent therapeutic approaches, including targeted therapy and immunotherapy, have improved the prognosis and outcome of melanoma patients. BRAF is one of the most frequently mutated oncogenes re...

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Veröffentlicht in:	Cancers 2023-08, Vol.15 (16), p.4026
Hauptverfasser:	Castellani, Giorgia, Buccarelli, Mariachiara, Arasi, Maria Beatrice, Rossi, Stefania, Pisanu, Maria Elena, Bellenghi, Maria, Lintas, Carla, Tabolacci, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological markers Biomarkers Cancer Care and treatment Codon DNA methylation Gene mutations Genetic aspects Genetic transformation Genetically modified organisms Health aspects Immunotherapy Inflammation Kinases MAP kinase Melanocytes Melanoma Metastasis Mutation Point mutation Review Signal transduction Skin Skin cancer Tumors
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