Identifying Significantly Perturbed Subnetworks in Cancer Using Multiple Protein-Protein Interaction Networks

The identification of cancer driver genes and key molecular pathways has been the focus of large-scale cancer genome studies. Network-based methods detect significantly perturbed subnetworks as putative cancer pathways by incorporating genomics data with the topological information of PPI networks....

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Veröffentlicht in:	Cancers 2023-08, Vol.15 (16), p.4090
Hauptverfasser:	Yang, Le, Chen, Runpu, Melendy, Thomas, Goodison, Steve, Sun, Yijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Genes Genomics Identification Linear programming Methods Mutation Proteins Seeds
Online-Zugang:	Volltext
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