A programmable pAgo nuclease with RNA target-cleavage specificity from the mesophilic bacterium Verrucomicrobia: A pAgo with RNA target cleavage specificity

Argonaute (Ago) proteins are conserved programmable nucleases present in eukaryotes and prokaryotes and provide defense against mobile genetic elements. Almost all characterized pAgos prefer to cleave DNA targets. Here, we describe a novel pAgo from Verrucomicrobia bacterium (VbAgo) that can specifi...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2023-07, Vol.55 (8), p.1204-1212
Hauptverfasser:	Liu, Qi, Chen, Wanping, Zhang, Yue, Hu, Fengyang, Jiang, Xiaoman, Wang, Fei, Liu, Yang, Ma, Lixin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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