Protein Folding Stability Profiling of Colorectal Cancer Chemoresistance Identifies Functionally Relevant Biomarkers

Reported here is the application of three protein folding stability profiling techniques (including the stability of proteins from rates of oxidation, thermal protein profiling, and limited proteolysis approaches) to identify differentially stabilized proteins in six patient-derived colorectal cance...

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Veröffentlicht in:	Journal of proteome research 2023-06, Vol.22 (6), p.1923-1935
Hauptverfasser:	Quan, Baiyi, Bailey, Morgan A., Mantyh, John, Hsu, David S., Fitzgerald, Michael C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Cell Line, Tumor Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Disease Models, Animal Drug Resistance, Neoplasm - genetics Humans Oxaliplatin - pharmacology Oxaliplatin - therapeutic use Protein Folding
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