Uncoupling of Ca2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia

There are no treatments available for vascular dementia, the second-most common dementia syndrome, and patients decline rapidly after diagnosis. This syndrome is primarily due to hypertension and is associated with reduced cerebral blood flow (CBF). To explore this, we studied mechanisms of vascular...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2023-08, Vol.120 (33), p.e2307513120-e2307513120
Hauptverfasser:	Taylor, Jade L, Walsh, Katy R, Mosneag, Ioana-Emilia, Danby, Thea G E, Luka, Nadim, Chanda, Bishal, Schiessl, Ingo, Dunne, Ross A, Hill-Eubanks, David, Hennig, Grant W, Allan, Stuart M, Nelson, Mark T, Greenstein, Adam S, Pritchard, Harry A T
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!