Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery

Abstract Retinal pigment epithelium (RPE) is a critical cell monolayer forming the blood-retina-barrier (BRB) and a permeable bridge between the choriocapillaris and the retina. RPE is also crucial in maintaining photoreceptor function and for completing the visual cycle. Loss of the RPE is associat...

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Veröffentlicht in:Stem cells translational medicine 2023-08, Vol.12 (8), p.536-552
Hauptverfasser: Gupta, Santosh, Lytvynchuk, Lyubomyr, Ardan, Taras, Studenovska, Hana, Sharma, Ruchi, Faura, Georgina, Eide, Lars, Shanker Verma, Rama, Znaor, Ljubo, Erceg, Slaven, Stieger, Knut, Motlik, Jan, Petrovski, Goran, Bharti, Kapil
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Sprache:eng
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