Robust aversive effects of trace amine-associated receptor 1 activation in mice

Drugs that stimulate the trace amine-associated receptor 1 (TAAR1) are under clinical investigation as treatments for several neuropsychiatric disorders. Previous studies in a genetic mouse model of voluntary methamphetamine intake identified TAAR1, expressed by the Taar1 gene, as a critical mediato...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2023-09, Vol.48 (10), p.1446-1454
Hauptverfasser:	Shabani, Shkelzen, Houlton, Sydney, Ghimire, Bikalpa, Tonello, Derek, Reed, Cheryl, Baba, Harue, Aldrich, Sara, Phillips, Tamara J
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Alleles Animal models Animals Drug abuse Female Male Mental disorders Methamphetamine Mice Monoamine transporter Phenotypes Receptors, G-Protein-Coupled - agonists Receptors, G-Protein-Coupled - genetics
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