MRD as Biomarker for Response to Donor Lymphocyte Infusion after Allogeneic Hematopoietic Cell Transplantation in Patients with AML

Donor lymphocyte infusions (DLIs) can directly target leukemic cells through a graft-versus-leukemia effect and play a key role in the prevention and management of relapse after allogeneic hematopoietic cell transplantation (alloHCT). Predictors of response to DLIs are not well established. We evalu...

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Veröffentlicht in:	Cancers 2023-08, Vol.15 (15), p.3911
Hauptverfasser:	Teich, Katrin, Stadler, Michael, Gabdoulline, Razif, Kandarp, Jyoti, Wienecke, Clara, Heida, Bennet, Klement, Piroska, Büttner, Konstantin, Venturini, Letizia, Wichmann, Martin, Puppe, Wolfram, Schultze-Florey, Christian, Koenecke, Christian, Beutel, Gernot, Eder, Matthias, Ganser, Arnold, Heuser, Michael, Thol, Felicitas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Allografts Bioinformatics Biomarkers Blood Chemotherapy Error correction & detection Genes Genetic testing Graft versus host disease Graft-versus-leukemia reaction Hematopoietic stem cells Leukemia Lymphocytes Multivariate analysis Mutation Next-generation sequencing Patients Remission Signal transduction Transplantation Variables
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