N-3-pyridylmethyl-N'-p-nitrophenylurea ocular toxicity in man and rabbits

Ingestion of the rat poison N-3-pyridylmethyl-N'-p-nitrophenylurea (PNU) produced ocular toxicity in three humans and in an animal model, the Dutch Belted rabbit. The electroretinogram b wave was especially susceptible to the effects of the rodenticide, and the target tissue appeared to be the...

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Veröffentlicht in:	British journal of ophthalmology 1988-08, Vol.72 (8), p.584-590
Hauptverfasser:	Mindel, J S, Kharlamb, A B, Friedman, A H, Karam, J H, Stone, R D, Siegel, I M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Biological and medical sciences Electroretinography Eye Diseases - chemically induced Eye Diseases - physiopathology Eye Diseases - prevention & control Female Gentamicins - therapeutic use Humans Hypotension, Orthostatic - chemically induced Male Medical sciences Pesticides, fertilizers and other agrochemicals toxicology Phenylurea Compounds - antagonists & inhibitors Phenylurea Compounds - poisoning Phenylurea Compounds - toxicity Photoreceptor Cells - physiopathology Rabbits Retina - pathology Rodenticides - poisoning Rodenticides - toxicity Toxicology Tryptophan - administration & dosage Tryptophan - therapeutic use
Online-Zugang:	Volltext
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