Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents

There is an increasing need to evaluate innovative drugs for childhood cancer using combination strategies. Strong biological rationale and clinical experience suggest that multiple agents will be more efficacious than monotherapy for most diseases and may overcome resistance mechanisms and increase...

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Veröffentlicht in:	Journal of clinical oncology 2023-06, Vol.41 (18), p.3408-3422
Hauptverfasser:	Moreno, Lucas, DuBois, Steven G, Glade Bender, Julia, Mauguen, Audrey, Bird, Nick, Buenger, Vickie, Casanova, Michela, Doz, François, Fox, Elizabeth, Gore, Lia, Hawkins, Douglas S, Izraeli, Shai, Jones, David T W, Kearns, Pamela R, Molenaar, Jan J, Nysom, Karsten, Pfister, Stefan, Reaman, Gregory, Smith, Malcolm, Weigel, Brenda, Vassal, Gilles, Zwaan, Christian Michel, Paoletti, Xavier, Iasonos, Alexia, Pearson, Andrew D J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antineoplastic Agents - adverse effects Child Drug Development Humans Life Sciences Neoplasms - drug therapy Special
Online-Zugang:	Volltext
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