Apolipoprotein-ε4 is associated with higher fecundity in a natural fertility population

In many populations, the apolipoprotein-ε4 (APOE-ε4) allele increases the risk for several chronic diseases of aging, including dementia and cardiovascular disease; despite these harmful effects at later ages, the APOE-ε4 allele remains prevalent. We assess the impact of APOE-ε4 on fertility and its...

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Veröffentlicht in:Science advances 2023-08, Vol.9 (32), p.eade9797-eade9797
Hauptverfasser: Trumble, Benjamin C, Charifson, Mia, Kraft, Tom, Garcia, Angela R, Cummings, Daniel K, Hooper, Paul, Lea, Amanda J, Eid Rodriguez, Daniel, Koebele, Stephanie V, Buetow, Kenneth, Beheim, Bret, Minocher, Riana, Gutierrez, Maguin, Thomas, Gregory S, Gatz, Margaret, Stieglitz, Jonathan, Finch, Caleb E, Kaplan, Hillard, Gurven, Michael
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Sprache:eng
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