The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial
Purpose Patients with primary malignant brain tumors have high symptom burden and commonly rely on family caregivers for practical and emotional support. This can lead to negative mental and physical consequences for caregivers. We investigated effectiveness of an 8-week nurse-led online needs-based...
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| Veröffentlicht in: | Supportive care in cancer 2022-03, Vol.30 (3), p.2059-2068 |
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| creator | Boele, Florien W. Weimer, Jason M. Marsland, Anna L. Armstrong, Terri S. Given, Charles W. Drappatz, Jan Donovan, Heidi S. Sherwood, Paula R. |
| description | Purpose
Patients with primary malignant brain tumors have high symptom burden and commonly rely on family caregivers for practical and emotional support. This can lead to negative mental and physical consequences for caregivers. We investigated effectiveness of an 8-week nurse-led online needs-based support program (SmartCare
©
) with and without online self-guided cognitive behavioral therapy (CBT) for depression compared to enhanced care as usual (ECAU) on depressive symptoms, caregiving-specific distress, anxiety, mastery, and burden.
Methods
Family caregivers scoring ≥ 6 on a depressive symptoms inventory were randomized to three groups: ECAU plus self-guided CBT and SmartCare
©
; ECAU plus SmartCare
©
; ECAU only. Primary outcomes (depressive symptoms; caregiving-specific distress) and secondary outcomes (anxiety, caregiver mastery, and caregiver burden) were assessed online. Intention to treat (ITT) and per protocol (PP) analyses of covariance corrected for baseline scores were performed for outcomes at 4 months.
Results
In total, 120 family caregivers participated. Accrual and CBT engagement were lower than expected, therefore intervention groups were combined (
n
= 80) and compared to ECAU (
n
= 40). For depressive symptoms, no statistically significant group differences were found. Caregiving-specific distress decreased in the intervention group compared with ECAU (ITT:
p
= 0.01, partial
ɳ
2
= 0.08; PP:
p
= 0.02, partial
ɳ
2
= 0.08). A trend towards improvement in mastery for the intervention group compared with ECAU was identified (ITT:
p
= 0.08, partial
ɳ
2
= 0.04; PP:
p
= 0.07, partial
ɳ
2
= 0.05).
Conclusions
SmartCare
©
, with or without self-guided CBT, reduced caregiving-specific distress with a trend towards improving mastery. SmartCare
©
has the potential to improve the lives of families coping with a brain tumor diagnosis.
Trial registration number
NCT02058745; 10 February 2014 |
| doi_str_mv | 10.1007/s00520-021-06555-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10411320</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2582818073</sourcerecordid><originalsourceid>FETCH-LOGICAL-c475t-4c52ffccd242c3933c3811991ec8f539471e3894e97c9019b55a21dd2aef5d9f3</originalsourceid><addsrcrecordid>eNp9kUtuFDEURS0EIk3DBhggS0yYGPz86SozQajFT4rEgDC2HNdzx5GrHOyqSM2IbbAEtsFSWAmGDuEzYGRL97zrd30JuQ_8MXDePamca8EZF8D4RmvN9A2yAiUl66Q0N8mKGwVMSa2PyJ1azzmHrtPiNjmSqvFSbFYknpwhxRDQz5XmQN-NrsxbV_DrF5onOuFSMsuTzynv9jS4MaY99U3fxUss9dunz3SIdS5Y61PqaHHTkMf4EQfq8zSXnFK7ziW6dJfcCi5VvHd1rsn7ly9Otq_Z8dtXb7bPj5lXnZ6Z8lqE4P0glPDSSOllD2AMoO-DlkZ1gLI3Ck3nDQdzqrUTMAzCYdCDCXJNnh18L5bTEQePbQ2X7EWJLdreZhft38oUz-wuX1rgCkAK3hweXTmU_GHBOtsxVo8puQnzUq3Qveih5-2X1-ThP-h5XsrU8lmxERJMp3rRKHGgfMm1FgzX2wC3P6q0hyptq9L-rNLqNvTgzxzXI7-6a4A8ALVJ0w7L77f_Y_sdxVesog</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2623197482</pqid></control><display><type>article</type><title>The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Boele, Florien W. ; Weimer, Jason M. ; Marsland, Anna L. ; Armstrong, Terri S. ; Given, Charles W. ; Drappatz, Jan ; Donovan, Heidi S. ; Sherwood, Paula R.</creator><creatorcontrib>Boele, Florien W. ; Weimer, Jason M. ; Marsland, Anna L. ; Armstrong, Terri S. ; Given, Charles W. ; Drappatz, Jan ; Donovan, Heidi S. ; Sherwood, Paula R.</creatorcontrib><description>Purpose
Patients with primary malignant brain tumors have high symptom burden and commonly rely on family caregivers for practical and emotional support. This can lead to negative mental and physical consequences for caregivers. We investigated effectiveness of an 8-week nurse-led online needs-based support program (SmartCare
©
) with and without online self-guided cognitive behavioral therapy (CBT) for depression compared to enhanced care as usual (ECAU) on depressive symptoms, caregiving-specific distress, anxiety, mastery, and burden.
Methods
Family caregivers scoring ≥ 6 on a depressive symptoms inventory were randomized to three groups: ECAU plus self-guided CBT and SmartCare
©
; ECAU plus SmartCare
©
; ECAU only. Primary outcomes (depressive symptoms; caregiving-specific distress) and secondary outcomes (anxiety, caregiver mastery, and caregiver burden) were assessed online. Intention to treat (ITT) and per protocol (PP) analyses of covariance corrected for baseline scores were performed for outcomes at 4 months.
Results
In total, 120 family caregivers participated. Accrual and CBT engagement were lower than expected, therefore intervention groups were combined (
n
= 80) and compared to ECAU (
n
= 40). For depressive symptoms, no statistically significant group differences were found. Caregiving-specific distress decreased in the intervention group compared with ECAU (ITT:
p
= 0.01, partial
ɳ
2
= 0.08; PP:
p
= 0.02, partial
ɳ
2
= 0.08). A trend towards improvement in mastery for the intervention group compared with ECAU was identified (ITT:
p
= 0.08, partial
ɳ
2
= 0.04; PP:
p
= 0.07, partial
ɳ
2
= 0.05).
Conclusions
SmartCare
©
, with or without self-guided CBT, reduced caregiving-specific distress with a trend towards improving mastery. SmartCare
©
has the potential to improve the lives of families coping with a brain tumor diagnosis.
Trial registration number
NCT02058745; 10 February 2014</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-021-06555-5</identifier><identifier>PMID: 34655326</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adaptation, Psychological ; Anxiety ; Anxiety - therapy ; Behavior modification ; Brain cancer ; Brain Neoplasms ; Caregivers ; Clinical trials ; Cognitive Behavioral Therapy ; Cognitive therapy ; Humans ; Medicine ; Medicine & Public Health ; Mental depression ; Mental health ; Nursing ; Nursing care ; Nursing Research ; Oncology ; Original Article ; Pain Medicine ; Quality of Life ; Rehabilitation Medicine</subject><ispartof>Supportive care in cancer, 2022-03, Vol.30 (3), p.2059-2068</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2022</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2022.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-4c52ffccd242c3933c3811991ec8f539471e3894e97c9019b55a21dd2aef5d9f3</citedby><cites>FETCH-LOGICAL-c475t-4c52ffccd242c3933c3811991ec8f539471e3894e97c9019b55a21dd2aef5d9f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-021-06555-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-021-06555-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34655326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boele, Florien W.</creatorcontrib><creatorcontrib>Weimer, Jason M.</creatorcontrib><creatorcontrib>Marsland, Anna L.</creatorcontrib><creatorcontrib>Armstrong, Terri S.</creatorcontrib><creatorcontrib>Given, Charles W.</creatorcontrib><creatorcontrib>Drappatz, Jan</creatorcontrib><creatorcontrib>Donovan, Heidi S.</creatorcontrib><creatorcontrib>Sherwood, Paula R.</creatorcontrib><title>The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description>Purpose
Patients with primary malignant brain tumors have high symptom burden and commonly rely on family caregivers for practical and emotional support. This can lead to negative mental and physical consequences for caregivers. We investigated effectiveness of an 8-week nurse-led online needs-based support program (SmartCare
©
) with and without online self-guided cognitive behavioral therapy (CBT) for depression compared to enhanced care as usual (ECAU) on depressive symptoms, caregiving-specific distress, anxiety, mastery, and burden.
Methods
Family caregivers scoring ≥ 6 on a depressive symptoms inventory were randomized to three groups: ECAU plus self-guided CBT and SmartCare
©
; ECAU plus SmartCare
©
; ECAU only. Primary outcomes (depressive symptoms; caregiving-specific distress) and secondary outcomes (anxiety, caregiver mastery, and caregiver burden) were assessed online. Intention to treat (ITT) and per protocol (PP) analyses of covariance corrected for baseline scores were performed for outcomes at 4 months.
Results
In total, 120 family caregivers participated. Accrual and CBT engagement were lower than expected, therefore intervention groups were combined (
n
= 80) and compared to ECAU (
n
= 40). For depressive symptoms, no statistically significant group differences were found. Caregiving-specific distress decreased in the intervention group compared with ECAU (ITT:
p
= 0.01, partial
ɳ
2
= 0.08; PP:
p
= 0.02, partial
ɳ
2
= 0.08). A trend towards improvement in mastery for the intervention group compared with ECAU was identified (ITT:
p
= 0.08, partial
ɳ
2
= 0.04; PP:
p
= 0.07, partial
ɳ
2
= 0.05).
Conclusions
SmartCare
©
, with or without self-guided CBT, reduced caregiving-specific distress with a trend towards improving mastery. SmartCare
©
has the potential to improve the lives of families coping with a brain tumor diagnosis.
Trial registration number
NCT02058745; 10 February 2014</description><subject>Adaptation, Psychological</subject><subject>Anxiety</subject><subject>Anxiety - therapy</subject><subject>Behavior modification</subject><subject>Brain cancer</subject><subject>Brain Neoplasms</subject><subject>Caregivers</subject><subject>Clinical trials</subject><subject>Cognitive Behavioral Therapy</subject><subject>Cognitive therapy</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental depression</subject><subject>Mental health</subject><subject>Nursing</subject><subject>Nursing care</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pain Medicine</subject><subject>Quality of Life</subject><subject>Rehabilitation Medicine</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUtuFDEURS0EIk3DBhggS0yYGPz86SozQajFT4rEgDC2HNdzx5GrHOyqSM2IbbAEtsFSWAmGDuEzYGRL97zrd30JuQ_8MXDePamca8EZF8D4RmvN9A2yAiUl66Q0N8mKGwVMSa2PyJ1azzmHrtPiNjmSqvFSbFYknpwhxRDQz5XmQN-NrsxbV_DrF5onOuFSMsuTzynv9jS4MaY99U3fxUss9dunz3SIdS5Y61PqaHHTkMf4EQfq8zSXnFK7ziW6dJfcCi5VvHd1rsn7ly9Otq_Z8dtXb7bPj5lXnZ6Z8lqE4P0glPDSSOllD2AMoO-DlkZ1gLI3Ck3nDQdzqrUTMAzCYdCDCXJNnh18L5bTEQePbQ2X7EWJLdreZhft38oUz-wuX1rgCkAK3hweXTmU_GHBOtsxVo8puQnzUq3Qveih5-2X1-ThP-h5XsrU8lmxERJMp3rRKHGgfMm1FgzX2wC3P6q0hyptq9L-rNLqNvTgzxzXI7-6a4A8ALVJ0w7L77f_Y_sdxVesog</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Boele, Florien W.</creator><creator>Weimer, Jason M.</creator><creator>Marsland, Anna L.</creator><creator>Armstrong, Terri S.</creator><creator>Given, Charles W.</creator><creator>Drappatz, Jan</creator><creator>Donovan, Heidi S.</creator><creator>Sherwood, Paula R.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220301</creationdate><title>The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial</title><author>Boele, Florien W. ; Weimer, Jason M. ; Marsland, Anna L. ; Armstrong, Terri S. ; Given, Charles W. ; Drappatz, Jan ; Donovan, Heidi S. ; Sherwood, Paula R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-4c52ffccd242c3933c3811991ec8f539471e3894e97c9019b55a21dd2aef5d9f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adaptation, Psychological</topic><topic>Anxiety</topic><topic>Anxiety - therapy</topic><topic>Behavior modification</topic><topic>Brain cancer</topic><topic>Brain Neoplasms</topic><topic>Caregivers</topic><topic>Clinical trials</topic><topic>Cognitive Behavioral Therapy</topic><topic>Cognitive therapy</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental depression</topic><topic>Mental health</topic><topic>Nursing</topic><topic>Nursing care</topic><topic>Nursing Research</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Pain Medicine</topic><topic>Quality of Life</topic><topic>Rehabilitation Medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boele, Florien W.</creatorcontrib><creatorcontrib>Weimer, Jason M.</creatorcontrib><creatorcontrib>Marsland, Anna L.</creatorcontrib><creatorcontrib>Armstrong, Terri S.</creatorcontrib><creatorcontrib>Given, Charles W.</creatorcontrib><creatorcontrib>Drappatz, Jan</creatorcontrib><creatorcontrib>Donovan, Heidi S.</creatorcontrib><creatorcontrib>Sherwood, Paula R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Supportive care in cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boele, Florien W.</au><au>Weimer, Jason M.</au><au>Marsland, Anna L.</au><au>Armstrong, Terri S.</au><au>Given, Charles W.</au><au>Drappatz, Jan</au><au>Donovan, Heidi S.</au><au>Sherwood, Paula R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial</atitle><jtitle>Supportive care in cancer</jtitle><stitle>Support Care Cancer</stitle><addtitle>Support Care Cancer</addtitle><date>2022-03-01</date><risdate>2022</risdate><volume>30</volume><issue>3</issue><spage>2059</spage><epage>2068</epage><pages>2059-2068</pages><issn>0941-4355</issn><eissn>1433-7339</eissn><abstract>Purpose
Patients with primary malignant brain tumors have high symptom burden and commonly rely on family caregivers for practical and emotional support. This can lead to negative mental and physical consequences for caregivers. We investigated effectiveness of an 8-week nurse-led online needs-based support program (SmartCare
©
) with and without online self-guided cognitive behavioral therapy (CBT) for depression compared to enhanced care as usual (ECAU) on depressive symptoms, caregiving-specific distress, anxiety, mastery, and burden.
Methods
Family caregivers scoring ≥ 6 on a depressive symptoms inventory were randomized to three groups: ECAU plus self-guided CBT and SmartCare
©
; ECAU plus SmartCare
©
; ECAU only. Primary outcomes (depressive symptoms; caregiving-specific distress) and secondary outcomes (anxiety, caregiver mastery, and caregiver burden) were assessed online. Intention to treat (ITT) and per protocol (PP) analyses of covariance corrected for baseline scores were performed for outcomes at 4 months.
Results
In total, 120 family caregivers participated. Accrual and CBT engagement were lower than expected, therefore intervention groups were combined (
n
= 80) and compared to ECAU (
n
= 40). For depressive symptoms, no statistically significant group differences were found. Caregiving-specific distress decreased in the intervention group compared with ECAU (ITT:
p
= 0.01, partial
ɳ
2
= 0.08; PP:
p
= 0.02, partial
ɳ
2
= 0.08). A trend towards improvement in mastery for the intervention group compared with ECAU was identified (ITT:
p
= 0.08, partial
ɳ
2
= 0.04; PP:
p
= 0.07, partial
ɳ
2
= 0.05).
Conclusions
SmartCare
©
, with or without self-guided CBT, reduced caregiving-specific distress with a trend towards improving mastery. SmartCare
©
has the potential to improve the lives of families coping with a brain tumor diagnosis.
Trial registration number
NCT02058745; 10 February 2014</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34655326</pmid><doi>10.1007/s00520-021-06555-5</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0941-4355 |
| ispartof | Supportive care in cancer, 2022-03, Vol.30 (3), p.2059-2068 |
| issn | 0941-4355 1433-7339 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10411320 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Adaptation, Psychological Anxiety Anxiety - therapy Behavior modification Brain cancer Brain Neoplasms Caregivers Clinical trials Cognitive Behavioral Therapy Cognitive therapy Humans Medicine Medicine & Public Health Mental depression Mental health Nursing Nursing care Nursing Research Oncology Original Article Pain Medicine Quality of Life Rehabilitation Medicine |
| title | The effects of SmartCare© on neuro-oncology family caregivers’ distress: a randomized controlled trial |
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