GSKIP modulates cell aggregation through EMT/MET signaling rather than differentiation in SH-SY5Y human neuroblastoma cells

GSK3β interacting protein (GSKIP) is a small A-kinase anchor protein previously reported to mediate the N-cadherin/β-catenin pool for differentiation in SH-SY5Y cells through overexpression of GSKIP to present the neuron outgrowth phenotype. To further investigate how GSKIP functions in neurons, CRI...

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Veröffentlicht in:	Journal of cell communication and signaling 2023-09, Vol.17 (3), p.1039-1054
Hauptverfasser:	Tsai, Cheng-Yu, Ko, Huey-Jiun, Chiou, Shean-Jaw, Lin, Xin-Yi, Chuang, Tsung-Hsien, Cheng, Jiin-Tsuey, Su, Yu-Feng, Loh, Joon-Khim, Hong, Yi-Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine c-Met protein Cadherins Cell adhesion & migration Cell aggregation Cell Biology Cell cycle Cell differentiation Cell migration Cell survival Cloning CRISPR EMT/MET Gene set enrichment analysis Genotype & phenotype GSKIP Harsh environments Kinases Life Sciences N-Cadherin Neuroblastoma cells Phenotypes Phosphor‐β‐catenin Proliferation Research Article Retinoic acid Signal transduction Tumorigenesis Wnt protein Wnt/β‐catenin β-Catenin
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