Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction
Aims: Coronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully disc...
Gespeichert in:
Veröffentlicht in: | Journal of Atherosclerosis and Thrombosis 2023/08/01, Vol.30(8), pp.990-1001 |
---|---|
Hauptverfasser: | , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1001 |
---|---|
container_issue | 8 |
container_start_page | 990 |
container_title | Journal of Atherosclerosis and Thrombosis |
container_volume | 30 |
creator | Ishibashi, Shun Sakakura, Kenichi Asada, Satoshi Taniguchi, Yousuke Jinnouchi, Hiroyuki Tsukui, Takunori Watanabe, Yusuke Yamamoto, Kei Seguchi, Masaru Wada, Hiroshi Fujita, Hideo |
description | Aims: Coronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully discussed. The purpose of this retrospective study was to assess the usefulness of angiographic coronary calcification as a risk marker for long-term clinical outcomes following percutaneous coronary intervention to the culprit lesions of AMI. Methods: We included 1209 patients with AMI and divided them into the none–mild calcification group (n=923) and the moderate–severe calcification group (n=286) according to angiographic coronary calcification in the culprit lesion of AMI. The primary endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of all-cause death, nonfatal MI, readmission for heart failure, and ischemia-driven target vessel revascularization. Results: The median follow-up duration was 542 (Q1: 182, Q3: 990) days. A total of 345 MACE were observed during the study period. The occurrence of MACE was significantly greater in the moderate–severe calcification group than in the none–mild calcification group (43.4% vs. 23.9%, p<0.001). In the multivariate Cox hazard model, moderate–severe calcification was significantly associated with MACE (hazard ratio 1.302, 95% confidence interval 1.011–1.677, p=0.041) after controlling multiple confounding factors. Conclusions: Angiographically moderate to severe calcification in AMI culprit lesion was associated with long-term worse clinical outcomes. Angiographic coronary calcification can be a simple risk marker in patients after AMI. |
doi_str_mv | 10.5551/jat.63856 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10406646</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2728144672</sourcerecordid><originalsourceid>FETCH-LOGICAL-c452t-de6c78e30aba9ca9bea98276a637564ccf616951707be1e81bf7379c8fe63e183</originalsourceid><addsrcrecordid>eNpVkU1v1DAQhiMEoqVw4A8gH-GQYseJ7XBBq4iPSotaiXK2nNlJ1qvEXmwH1DN_HO-2LHCxR5rHz4z1FsVLRi-bpmFvdyZdCq4a8ag4Z0rRkivJH-ea17mupTornsW4o5TzpqmeFmdcVJK3TJ4Xv1ZutH4MZr-1QDofvDPhjnRmAjtYMMl6946syFc77yckNwE3FpIPxA9k7d1Y3mKYSTdZl-GJXC8J_IyRWEdu8mN0KZKfNm3JCpaE5MudBxM2NqNXbjABDv7nxZPBTBFfPNwXxbePH267z-X6-tNVt1qXUDdVKjcoQCrk1PSmBdP2aFpVSWEEl42oAQbBRNswSWWPDBXrB8llC2pAwZEpflG8v_ful37GDeTlgpn0Ptg5_1l7Y_X_HWe3evQ_NKM1FaIW2fD6wRD89wVj0rONgNNkHPol6kpWitW1kFVG39yjEHyMAYfTHEb1ITWdU9PH1DL76t_FTuSfmP5uvovJjHgCTEgWJjyqONXqcByVpw5sTdDo-G9y26ye</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2728144672</pqid></control><display><type>article</type><title>Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction</title><source>J-STAGE Free</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Ishibashi, Shun ; Sakakura, Kenichi ; Asada, Satoshi ; Taniguchi, Yousuke ; Jinnouchi, Hiroyuki ; Tsukui, Takunori ; Watanabe, Yusuke ; Yamamoto, Kei ; Seguchi, Masaru ; Wada, Hiroshi ; Fujita, Hideo</creator><creatorcontrib>Ishibashi, Shun ; Sakakura, Kenichi ; Asada, Satoshi ; Taniguchi, Yousuke ; Jinnouchi, Hiroyuki ; Tsukui, Takunori ; Watanabe, Yusuke ; Yamamoto, Kei ; Seguchi, Masaru ; Wada, Hiroshi ; Fujita, Hideo</creatorcontrib><description>Aims: Coronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully discussed. The purpose of this retrospective study was to assess the usefulness of angiographic coronary calcification as a risk marker for long-term clinical outcomes following percutaneous coronary intervention to the culprit lesions of AMI. Methods: We included 1209 patients with AMI and divided them into the none–mild calcification group (n=923) and the moderate–severe calcification group (n=286) according to angiographic coronary calcification in the culprit lesion of AMI. The primary endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of all-cause death, nonfatal MI, readmission for heart failure, and ischemia-driven target vessel revascularization. Results: The median follow-up duration was 542 (Q1: 182, Q3: 990) days. A total of 345 MACE were observed during the study period. The occurrence of MACE was significantly greater in the moderate–severe calcification group than in the none–mild calcification group (43.4% vs. 23.9%, p<0.001). In the multivariate Cox hazard model, moderate–severe calcification was significantly associated with MACE (hazard ratio 1.302, 95% confidence interval 1.011–1.677, p=0.041) after controlling multiple confounding factors. Conclusions: Angiographically moderate to severe calcification in AMI culprit lesion was associated with long-term worse clinical outcomes. Angiographic coronary calcification can be a simple risk marker in patients after AMI.</description><identifier>ISSN: 1340-3478</identifier><identifier>EISSN: 1880-3873</identifier><identifier>DOI: 10.5551/jat.63856</identifier><identifier>PMID: 36273917</identifier><language>eng</language><publisher>Japan: Japan Atherosclerosis Society</publisher><subject>Acute myocardial infarction ; Angiographic coronary calcification ; Calcinosis - complications ; Coronary Angiography - adverse effects ; Coronary Artery Disease - complications ; Humans ; Major adverse cardiac events ; Myocardial Infarction - etiology ; Original ; Percutaneous coronary intervention ; Percutaneous Coronary Intervention - adverse effects ; Retrospective Studies ; Risk Factors ; Treatment Outcome</subject><ispartof>Journal of Atherosclerosis and Thrombosis, 2023/08/01, Vol.30(8), pp.990-1001</ispartof><rights>This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.</rights><rights>2023 Japan Atherosclerosis Society 2023</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-de6c78e30aba9ca9bea98276a637564ccf616951707be1e81bf7379c8fe63e183</citedby><cites>FETCH-LOGICAL-c452t-de6c78e30aba9ca9bea98276a637564ccf616951707be1e81bf7379c8fe63e183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406646/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406646/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,1883,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36273917$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ishibashi, Shun</creatorcontrib><creatorcontrib>Sakakura, Kenichi</creatorcontrib><creatorcontrib>Asada, Satoshi</creatorcontrib><creatorcontrib>Taniguchi, Yousuke</creatorcontrib><creatorcontrib>Jinnouchi, Hiroyuki</creatorcontrib><creatorcontrib>Tsukui, Takunori</creatorcontrib><creatorcontrib>Watanabe, Yusuke</creatorcontrib><creatorcontrib>Yamamoto, Kei</creatorcontrib><creatorcontrib>Seguchi, Masaru</creatorcontrib><creatorcontrib>Wada, Hiroshi</creatorcontrib><creatorcontrib>Fujita, Hideo</creatorcontrib><title>Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction</title><title>Journal of Atherosclerosis and Thrombosis</title><addtitle>JAT</addtitle><description>Aims: Coronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully discussed. The purpose of this retrospective study was to assess the usefulness of angiographic coronary calcification as a risk marker for long-term clinical outcomes following percutaneous coronary intervention to the culprit lesions of AMI. Methods: We included 1209 patients with AMI and divided them into the none–mild calcification group (n=923) and the moderate–severe calcification group (n=286) according to angiographic coronary calcification in the culprit lesion of AMI. The primary endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of all-cause death, nonfatal MI, readmission for heart failure, and ischemia-driven target vessel revascularization. Results: The median follow-up duration was 542 (Q1: 182, Q3: 990) days. A total of 345 MACE were observed during the study period. The occurrence of MACE was significantly greater in the moderate–severe calcification group than in the none–mild calcification group (43.4% vs. 23.9%, p<0.001). In the multivariate Cox hazard model, moderate–severe calcification was significantly associated with MACE (hazard ratio 1.302, 95% confidence interval 1.011–1.677, p=0.041) after controlling multiple confounding factors. Conclusions: Angiographically moderate to severe calcification in AMI culprit lesion was associated with long-term worse clinical outcomes. Angiographic coronary calcification can be a simple risk marker in patients after AMI.</description><subject>Acute myocardial infarction</subject><subject>Angiographic coronary calcification</subject><subject>Calcinosis - complications</subject><subject>Coronary Angiography - adverse effects</subject><subject>Coronary Artery Disease - complications</subject><subject>Humans</subject><subject>Major adverse cardiac events</subject><subject>Myocardial Infarction - etiology</subject><subject>Original</subject><subject>Percutaneous coronary intervention</subject><subject>Percutaneous Coronary Intervention - adverse effects</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><issn>1340-3478</issn><issn>1880-3873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1v1DAQhiMEoqVw4A8gH-GQYseJ7XBBq4iPSotaiXK2nNlJ1qvEXmwH1DN_HO-2LHCxR5rHz4z1FsVLRi-bpmFvdyZdCq4a8ag4Z0rRkivJH-ea17mupTornsW4o5TzpqmeFmdcVJK3TJ4Xv1ZutH4MZr-1QDofvDPhjnRmAjtYMMl6946syFc77yckNwE3FpIPxA9k7d1Y3mKYSTdZl-GJXC8J_IyRWEdu8mN0KZKfNm3JCpaE5MudBxM2NqNXbjABDv7nxZPBTBFfPNwXxbePH267z-X6-tNVt1qXUDdVKjcoQCrk1PSmBdP2aFpVSWEEl42oAQbBRNswSWWPDBXrB8llC2pAwZEpflG8v_ful37GDeTlgpn0Ptg5_1l7Y_X_HWe3evQ_NKM1FaIW2fD6wRD89wVj0rONgNNkHPol6kpWitW1kFVG39yjEHyMAYfTHEb1ITWdU9PH1DL76t_FTuSfmP5uvovJjHgCTEgWJjyqONXqcByVpw5sTdDo-G9y26ye</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>Ishibashi, Shun</creator><creator>Sakakura, Kenichi</creator><creator>Asada, Satoshi</creator><creator>Taniguchi, Yousuke</creator><creator>Jinnouchi, Hiroyuki</creator><creator>Tsukui, Takunori</creator><creator>Watanabe, Yusuke</creator><creator>Yamamoto, Kei</creator><creator>Seguchi, Masaru</creator><creator>Wada, Hiroshi</creator><creator>Fujita, Hideo</creator><general>Japan Atherosclerosis Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230801</creationdate><title>Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction</title><author>Ishibashi, Shun ; Sakakura, Kenichi ; Asada, Satoshi ; Taniguchi, Yousuke ; Jinnouchi, Hiroyuki ; Tsukui, Takunori ; Watanabe, Yusuke ; Yamamoto, Kei ; Seguchi, Masaru ; Wada, Hiroshi ; Fujita, Hideo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-de6c78e30aba9ca9bea98276a637564ccf616951707be1e81bf7379c8fe63e183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acute myocardial infarction</topic><topic>Angiographic coronary calcification</topic><topic>Calcinosis - complications</topic><topic>Coronary Angiography - adverse effects</topic><topic>Coronary Artery Disease - complications</topic><topic>Humans</topic><topic>Major adverse cardiac events</topic><topic>Myocardial Infarction - etiology</topic><topic>Original</topic><topic>Percutaneous coronary intervention</topic><topic>Percutaneous Coronary Intervention - adverse effects</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Treatment Outcome</topic><toplevel>online_resources</toplevel><creatorcontrib>Ishibashi, Shun</creatorcontrib><creatorcontrib>Sakakura, Kenichi</creatorcontrib><creatorcontrib>Asada, Satoshi</creatorcontrib><creatorcontrib>Taniguchi, Yousuke</creatorcontrib><creatorcontrib>Jinnouchi, Hiroyuki</creatorcontrib><creatorcontrib>Tsukui, Takunori</creatorcontrib><creatorcontrib>Watanabe, Yusuke</creatorcontrib><creatorcontrib>Yamamoto, Kei</creatorcontrib><creatorcontrib>Seguchi, Masaru</creatorcontrib><creatorcontrib>Wada, Hiroshi</creatorcontrib><creatorcontrib>Fujita, Hideo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Atherosclerosis and Thrombosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ishibashi, Shun</au><au>Sakakura, Kenichi</au><au>Asada, Satoshi</au><au>Taniguchi, Yousuke</au><au>Jinnouchi, Hiroyuki</au><au>Tsukui, Takunori</au><au>Watanabe, Yusuke</au><au>Yamamoto, Kei</au><au>Seguchi, Masaru</au><au>Wada, Hiroshi</au><au>Fujita, Hideo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction</atitle><jtitle>Journal of Atherosclerosis and Thrombosis</jtitle><addtitle>JAT</addtitle><date>2023-08-01</date><risdate>2023</risdate><volume>30</volume><issue>8</issue><spage>990</spage><epage>1001</epage><pages>990-1001</pages><artnum>63856</artnum><issn>1340-3478</issn><eissn>1880-3873</eissn><abstract>Aims: Coronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully discussed. The purpose of this retrospective study was to assess the usefulness of angiographic coronary calcification as a risk marker for long-term clinical outcomes following percutaneous coronary intervention to the culprit lesions of AMI. Methods: We included 1209 patients with AMI and divided them into the none–mild calcification group (n=923) and the moderate–severe calcification group (n=286) according to angiographic coronary calcification in the culprit lesion of AMI. The primary endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of all-cause death, nonfatal MI, readmission for heart failure, and ischemia-driven target vessel revascularization. Results: The median follow-up duration was 542 (Q1: 182, Q3: 990) days. A total of 345 MACE were observed during the study period. The occurrence of MACE was significantly greater in the moderate–severe calcification group than in the none–mild calcification group (43.4% vs. 23.9%, p<0.001). In the multivariate Cox hazard model, moderate–severe calcification was significantly associated with MACE (hazard ratio 1.302, 95% confidence interval 1.011–1.677, p=0.041) after controlling multiple confounding factors. Conclusions: Angiographically moderate to severe calcification in AMI culprit lesion was associated with long-term worse clinical outcomes. Angiographic coronary calcification can be a simple risk marker in patients after AMI.</abstract><cop>Japan</cop><pub>Japan Atherosclerosis Society</pub><pmid>36273917</pmid><doi>10.5551/jat.63856</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1340-3478 |
ispartof | Journal of Atherosclerosis and Thrombosis, 2023/08/01, Vol.30(8), pp.990-1001 |
issn | 1340-3478 1880-3873 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10406646 |
source | J-STAGE Free; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Acute myocardial infarction Angiographic coronary calcification Calcinosis - complications Coronary Angiography - adverse effects Coronary Artery Disease - complications Humans Major adverse cardiac events Myocardial Infarction - etiology Original Percutaneous coronary intervention Percutaneous Coronary Intervention - adverse effects Retrospective Studies Risk Factors Treatment Outcome |
title | Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T10%3A56%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Angiographic%20Coronary%20Calcification:%20A%20Simple%20Predictor%20of%20Long-Term%20Clinical%20Outcomes%20in%20Patients%20with%20Acute%20Myocardial%20Infarction&rft.jtitle=Journal%20of%20Atherosclerosis%20and%20Thrombosis&rft.au=Ishibashi,%20Shun&rft.date=2023-08-01&rft.volume=30&rft.issue=8&rft.spage=990&rft.epage=1001&rft.pages=990-1001&rft.artnum=63856&rft.issn=1340-3478&rft.eissn=1880-3873&rft_id=info:doi/10.5551/jat.63856&rft_dat=%3Cproquest_pubme%3E2728144672%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2728144672&rft_id=info:pmid/36273917&rfr_iscdi=true |