The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods
Abstract In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, tre...
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Veröffentlicht in: | Pain medicine (Malden, Mass.) Mass.), 2023-08, Vol.24 (Supplement_1), p.S3-S12 |
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creator | Mauck, Matthew C Lotz, Jeffrey Psioda, Matthew A Carey, Timothy S Clauw, Daniel J Majumdar, Sharmila Marras, William S Vo, Nam Aylward, Ayleen Hoffmeyer, Anna Zheng, Patricia Ivanova, Anastasia McCumber, Micah Carson, Christiane Anstrom, Kevin J Bowden, Anton E Dalton, Diane Derr, Leslie Dufour, Jonathan Fields, Aaron J Fritz, Julie Hassett, Afton L Harte, Steven E Hue, Trisha F Krug, Roland Loggia, Marco L Mageswaran, Prasath McLean, Samuel A Mitchell, Ulrike H O’Neill, Conor Pedoia, Valentina Quirk, David Adam Rhon, Daniel I Rieke, Viola Shah, Lubdha Sowa, Gwendolyn Spiegel, Brennan Wasan, Ajay D Wey, Hsiao-Ying (Monica) LaVange, Lisa |
description | Abstract
In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program’s goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science. |
doi_str_mv | 10.1093/pm/pnac202 |
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In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program’s goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science.</description><identifier>ISSN: 1526-2375</identifier><identifier>EISSN: 1526-4637</identifier><identifier>DOI: 10.1093/pm/pnac202</identifier><identifier>PMID: 36622041</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Advisory Committees ; Analgesics, Opioid - therapeutic use ; Chronic Pain - epidemiology ; Humans ; Low Back Pain - diagnosis ; Low Back Pain - therapy ; Opioid-Related Disorders - epidemiology ; Opioid-Related Disorders - therapy ; Original ; Pain Measurement - methods ; Research Design</subject><ispartof>Pain medicine (Malden, Mass.), 2023-08, Vol.24 (Supplement_1), p.S3-S12</ispartof><rights>The Author(s) 2023. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. 2023</rights><rights>The Author(s) 2023. Published by Oxford University Press on behalf of the American Academy of Pain Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-631f054d151ec8431b07aa0f7e35c109f419426982832b639f8918941e2ba50d3</citedby><cites>FETCH-LOGICAL-c409t-631f054d151ec8431b07aa0f7e35c109f419426982832b639f8918941e2ba50d3</cites><orcidid>0000-0001-5922-5755 ; 0000-0003-2570-1180 ; 0000-0001-8510-9491 ; 0000-0002-6394-6077 ; 0000-0002-4320-990X ; 0000-0002-9654-0647 ; 0000-0003-3124-7551</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,1578,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36622041$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mauck, Matthew C</creatorcontrib><creatorcontrib>Lotz, Jeffrey</creatorcontrib><creatorcontrib>Psioda, Matthew A</creatorcontrib><creatorcontrib>Carey, Timothy S</creatorcontrib><creatorcontrib>Clauw, Daniel J</creatorcontrib><creatorcontrib>Majumdar, Sharmila</creatorcontrib><creatorcontrib>Marras, William S</creatorcontrib><creatorcontrib>Vo, Nam</creatorcontrib><creatorcontrib>Aylward, Ayleen</creatorcontrib><creatorcontrib>Hoffmeyer, Anna</creatorcontrib><creatorcontrib>Zheng, Patricia</creatorcontrib><creatorcontrib>Ivanova, Anastasia</creatorcontrib><creatorcontrib>McCumber, Micah</creatorcontrib><creatorcontrib>Carson, Christiane</creatorcontrib><creatorcontrib>Anstrom, Kevin J</creatorcontrib><creatorcontrib>Bowden, Anton E</creatorcontrib><creatorcontrib>Dalton, Diane</creatorcontrib><creatorcontrib>Derr, Leslie</creatorcontrib><creatorcontrib>Dufour, Jonathan</creatorcontrib><creatorcontrib>Fields, Aaron J</creatorcontrib><creatorcontrib>Fritz, Julie</creatorcontrib><creatorcontrib>Hassett, Afton L</creatorcontrib><creatorcontrib>Harte, Steven E</creatorcontrib><creatorcontrib>Hue, Trisha F</creatorcontrib><creatorcontrib>Krug, Roland</creatorcontrib><creatorcontrib>Loggia, Marco L</creatorcontrib><creatorcontrib>Mageswaran, Prasath</creatorcontrib><creatorcontrib>McLean, Samuel A</creatorcontrib><creatorcontrib>Mitchell, Ulrike H</creatorcontrib><creatorcontrib>O’Neill, Conor</creatorcontrib><creatorcontrib>Pedoia, Valentina</creatorcontrib><creatorcontrib>Quirk, David Adam</creatorcontrib><creatorcontrib>Rhon, Daniel I</creatorcontrib><creatorcontrib>Rieke, Viola</creatorcontrib><creatorcontrib>Shah, Lubdha</creatorcontrib><creatorcontrib>Sowa, Gwendolyn</creatorcontrib><creatorcontrib>Spiegel, Brennan</creatorcontrib><creatorcontrib>Wasan, Ajay D</creatorcontrib><creatorcontrib>Wey, Hsiao-Ying (Monica)</creatorcontrib><creatorcontrib>LaVange, Lisa</creatorcontrib><title>The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods</title><title>Pain medicine (Malden, Mass.)</title><addtitle>Pain Med</addtitle><description>Abstract
In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program’s goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science.</description><subject>Adult</subject><subject>Advisory Committees</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Chronic Pain - epidemiology</subject><subject>Humans</subject><subject>Low Back Pain - diagnosis</subject><subject>Low Back Pain - therapy</subject><subject>Opioid-Related Disorders - epidemiology</subject><subject>Opioid-Related Disorders - therapy</subject><subject>Original</subject><subject>Pain Measurement - methods</subject><subject>Research Design</subject><issn>1526-2375</issn><issn>1526-4637</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><sourceid>EIF</sourceid><recordid>eNp9kU1Lw0AQhhdRrFYv_gDZi1CltfuVTeJF2uAXVCxaz8t2s2lXm2zcTQT_vZHGUi-eZmAenpnhBeAEo0uMYjos82FZSEUQ2QEHOCB8wDgNd9ue0DDogEPv3xDCnEV0H3Qo54Qghg-AmC01HEv1DqfSFDCxhbeuMnUOe-NRMh0l5_BZey2dWsKpswsn8yv4UrlaVbXT_e2hsc5URvs-lEUKH3W1tKk_AnuZXHl93NYueL29mSX3g8nT3UMymgwUQ3E14BRnKGApDrBWEaN4jkIpURZqGqjmyYzhmBEeRySiZM5pnEUxjmKGNZnLAKW0C67X3rKe5zpVuqicXInSmVy6L2GlEX8nhVmKhf0UGDFESRw1hl5rcPaj1r4SufFKr1ay0Lb2goScRJjjIGzQizWqnPXe6WyzByPxE4koc9FG0sCn25dt0N8MGuBsDdi6_E_0DUihkyE</recordid><startdate>20230804</startdate><enddate>20230804</enddate><creator>Mauck, Matthew C</creator><creator>Lotz, Jeffrey</creator><creator>Psioda, Matthew A</creator><creator>Carey, Timothy S</creator><creator>Clauw, Daniel J</creator><creator>Majumdar, Sharmila</creator><creator>Marras, William S</creator><creator>Vo, Nam</creator><creator>Aylward, Ayleen</creator><creator>Hoffmeyer, Anna</creator><creator>Zheng, Patricia</creator><creator>Ivanova, Anastasia</creator><creator>McCumber, Micah</creator><creator>Carson, Christiane</creator><creator>Anstrom, Kevin J</creator><creator>Bowden, Anton E</creator><creator>Dalton, Diane</creator><creator>Derr, Leslie</creator><creator>Dufour, Jonathan</creator><creator>Fields, Aaron J</creator><creator>Fritz, Julie</creator><creator>Hassett, Afton L</creator><creator>Harte, Steven E</creator><creator>Hue, Trisha F</creator><creator>Krug, Roland</creator><creator>Loggia, Marco L</creator><creator>Mageswaran, Prasath</creator><creator>McLean, Samuel A</creator><creator>Mitchell, Ulrike H</creator><creator>O’Neill, Conor</creator><creator>Pedoia, Valentina</creator><creator>Quirk, David Adam</creator><creator>Rhon, Daniel I</creator><creator>Rieke, Viola</creator><creator>Shah, Lubdha</creator><creator>Sowa, Gwendolyn</creator><creator>Spiegel, Brennan</creator><creator>Wasan, Ajay D</creator><creator>Wey, Hsiao-Ying (Monica)</creator><creator>LaVange, Lisa</creator><general>Oxford University Press</general><scope>TOX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5922-5755</orcidid><orcidid>https://orcid.org/0000-0003-2570-1180</orcidid><orcidid>https://orcid.org/0000-0001-8510-9491</orcidid><orcidid>https://orcid.org/0000-0002-6394-6077</orcidid><orcidid>https://orcid.org/0000-0002-4320-990X</orcidid><orcidid>https://orcid.org/0000-0002-9654-0647</orcidid><orcidid>https://orcid.org/0000-0003-3124-7551</orcidid></search><sort><creationdate>20230804</creationdate><title>The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods</title><author>Mauck, Matthew C ; Lotz, Jeffrey ; Psioda, Matthew A ; Carey, Timothy S ; Clauw, Daniel J ; Majumdar, Sharmila ; Marras, William S ; Vo, Nam ; Aylward, Ayleen ; Hoffmeyer, Anna ; Zheng, Patricia ; Ivanova, Anastasia ; McCumber, Micah ; Carson, Christiane ; Anstrom, Kevin J ; Bowden, Anton E ; Dalton, Diane ; Derr, Leslie ; Dufour, Jonathan ; Fields, Aaron J ; Fritz, Julie ; Hassett, Afton L ; Harte, Steven E ; Hue, Trisha F ; Krug, Roland ; Loggia, Marco L ; Mageswaran, Prasath ; McLean, Samuel A ; Mitchell, Ulrike H ; O’Neill, Conor ; Pedoia, Valentina ; Quirk, David Adam ; Rhon, Daniel I ; Rieke, Viola ; Shah, Lubdha ; Sowa, Gwendolyn ; Spiegel, Brennan ; Wasan, Ajay D ; Wey, Hsiao-Ying (Monica) ; LaVange, Lisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-631f054d151ec8431b07aa0f7e35c109f419426982832b639f8918941e2ba50d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adult</topic><topic>Advisory Committees</topic><topic>Analgesics, Opioid - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Pain medicine (Malden, Mass.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mauck, Matthew C</au><au>Lotz, Jeffrey</au><au>Psioda, Matthew A</au><au>Carey, Timothy S</au><au>Clauw, Daniel J</au><au>Majumdar, Sharmila</au><au>Marras, William S</au><au>Vo, Nam</au><au>Aylward, Ayleen</au><au>Hoffmeyer, Anna</au><au>Zheng, Patricia</au><au>Ivanova, Anastasia</au><au>McCumber, Micah</au><au>Carson, Christiane</au><au>Anstrom, Kevin J</au><au>Bowden, Anton E</au><au>Dalton, Diane</au><au>Derr, Leslie</au><au>Dufour, Jonathan</au><au>Fields, Aaron J</au><au>Fritz, Julie</au><au>Hassett, Afton L</au><au>Harte, Steven E</au><au>Hue, Trisha F</au><au>Krug, Roland</au><au>Loggia, Marco L</au><au>Mageswaran, Prasath</au><au>McLean, Samuel A</au><au>Mitchell, Ulrike H</au><au>O’Neill, Conor</au><au>Pedoia, Valentina</au><au>Quirk, David Adam</au><au>Rhon, Daniel I</au><au>Rieke, Viola</au><au>Shah, Lubdha</au><au>Sowa, Gwendolyn</au><au>Spiegel, Brennan</au><au>Wasan, Ajay D</au><au>Wey, Hsiao-Ying (Monica)</au><au>LaVange, Lisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods</atitle><jtitle>Pain medicine (Malden, Mass.)</jtitle><addtitle>Pain Med</addtitle><date>2023-08-04</date><risdate>2023</risdate><volume>24</volume><issue>Supplement_1</issue><spage>S3</spage><epage>S12</epage><pages>S3-S12</pages><issn>1526-2375</issn><eissn>1526-4637</eissn><abstract>Abstract
In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program’s goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>36622041</pmid><doi>10.1093/pm/pnac202</doi><orcidid>https://orcid.org/0000-0001-5922-5755</orcidid><orcidid>https://orcid.org/0000-0003-2570-1180</orcidid><orcidid>https://orcid.org/0000-0001-8510-9491</orcidid><orcidid>https://orcid.org/0000-0002-6394-6077</orcidid><orcidid>https://orcid.org/0000-0002-4320-990X</orcidid><orcidid>https://orcid.org/0000-0002-9654-0647</orcidid><orcidid>https://orcid.org/0000-0003-3124-7551</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Alma/SFX Local Collection; Oxford Journals |
subjects | Adult Advisory Committees Analgesics, Opioid - therapeutic use Chronic Pain - epidemiology Humans Low Back Pain - diagnosis Low Back Pain - therapy Opioid-Related Disorders - epidemiology Opioid-Related Disorders - therapy Original Pain Measurement - methods Research Design |
title | The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods |
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