Cell Surface Labeling and Detection of Protein Tyrosine Kinase 7 via Covalent Aptamers

Covalent aptamers are novel biochemical tools for fast and selective transfer of labels to target proteins. Equipped with cleavable electrophiles, these nucleic acid probes enable the installation of functional handles onto native proteins. The high affinity and specificity with which aptamers bind...

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Veröffentlicht in:	Journal of the American Chemical Society 2023-08, Vol.145 (30), p.16458-16463
Hauptverfasser:	Albright, Savannah, Cacace, Mary, Tivon, Yaniv, Deiters, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers, Nucleotide - chemistry Cell Membrane - metabolism Lysine - metabolism Membrane Proteins - metabolism Protein-Tyrosine Kinases - metabolism SELEX Aptamer Technique
Online-Zugang:	Volltext
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