Klotho: A new therapeutic target in diabetic retinopathy?

Klotho (Kl) is considered an antiaging gene, mainly for the inhibition of the insulin-like growth factor-1 signaling. Kl exists as full-length transmembrane, which acts as co-receptor for fibroblast growth factor receptor, and in soluble forms (sKl). The sKl may exert pleiotropic effects on organs a...

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Veröffentlicht in:	World journal of diabetes 2023-07, Vol.14 (7), p.1027-1036
Hauptverfasser:	Puddu, Alessandra, Maggi, Davide Carlo
Format:	Artikel
Sprache:	eng
Schlagworte:	Minireviews
Online-Zugang:	Volltext
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