Src- and Abl-family kinases activate spleen tyrosine kinase to maximize phagocytosis and Leishmania infection

Leishmania spp. are obligate intracellular parasites that must be internalized by phagocytic cells to evade immune responses and cause disease. The uptake of both Leishmania promastigotes (insect-stage parasites) and amastigotes (proliferative-stage parasites in humans and mice) by phagocytes is tho...

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Veröffentlicht in:	Journal of cell science 2023-07, Vol.136 (14)
Hauptverfasser:	Ullah, Imran, Barrie, Umaru, Kernen, Rebecca M, Mamula, Emily T, Khuong, Francis Tho Huu, Booshehri, Laela M, Rhodes, Emma L, Bradford, James M, Datta, Arani, Wetzel, Dawn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans Leishmania Leishmaniasis - parasitology Macrophages Mice Parasites Phagocytosis Syk Kinase
Online-Zugang:	Volltext
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