Feasibility of repairing skin defects by VEGF165 gene‐modified iPS‐HFSCs seeded on a 3D printed scaffold containing astragalus polysaccharide

The preparation of biodegradable scaffolds loaded with cells and cytokine is a feature of tissue‐engineered skin. IPSCs‐based tissue‐engineered skin treatment for wound repair is worth exploring. Healthy human skin fibroblasts were collected and reprogrammed into iPSCs. After gene modification and i...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2023-08, Vol.27 (15), p.2136-2149
Hauptverfasser:	Du, Weibin, Hu, Jintao, Huang, Xiaolong, Wang, Zhenwei, Zhou, Huateng, Yang, Yadong, Hu, Huahui, Chen, Rongliang, Shen, Fuxiang, Quan, Renfu
Format:	Artikel
Sprache:	eng
Schlagworte:	3D printed degradable scaffold astragalus polysaccharide Biocompatibility CD200 antigen Cell growth Cell proliferation Chinese medicine Cloning Collagen Cytokines Cytology Efficiency Epidermal growth factor Fibroblasts hair follicle stem cells Immunofluorescence Immunohistochemistry induced pluripotent stem cells Medical dressings Original Phenotypes Polysaccharides Proteins regeneration and repair Scanning electron microscopy Skin skin defect Stem cells Structure-function relationships Tissue engineering Transplantation Trauma Vascularization Wound healing
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