P1 Glutamine isosteres in the design of inhibitors of 3C/3CL protease of human viruses of the Pisoniviricetes class

Viral infections are one of the leading causes of acute morbidity in humans and much endeavour has been made by the synthetic community for the development of drugs to treat associated diseases. Peptide-based enzyme inhibitors, usually short sequences of three or four residues, are one of the classe...

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Veröffentlicht in:	RSC chemical biology 2023-08, Vol.4 (8), p.533-547
Hauptverfasser:	Stubbing, Louise A, Hubert, Jonathan G, Bell-Tyrer, Joseph, Hermant, Yann O, Yang, Sung Hyun, McSweeney, Alice M, McKenzie-Goldsmith, Geena M, Ward, Vernon K, Furkert, Daniel P, Brimble, Margaret A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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