Lactate shuttling drives the browning of white adipose tissue after burn

High levels of plasma lactate are associated with increased mortality in critically injured patients, including those with severe burns. Although lactate has long been considered a waste product of glycolysis, it was recently revealed that it acts as a potent inducer of white adipose tissue (WAT) br...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2023-09, Vol.325 (3), p.E180-E191
Hauptverfasser: Barayan, Dalia, Abdullahi, Abdikarim, Knuth, Carly M, Khalaf, Fadi, Rehou, Sarah, Screaton, Robert A, Jeschke, Marc G
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Sprache:eng
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