Mortality Associations With DNA Methylation-Based Biological Aging and Physical Functioning Measures Across a 20-Year Follow-up Period

Abstract Background Measures of biological aging range from DNA methylation (DNAm)-based estimates to measures of physical abilities. The purpose of this study was to compare DNAm- and physical functioning-based measures of biological aging in predicting mortality. Methods We studied 63- to 76-year-...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2023-08, Vol.78 (8), p.1489-1496
Hauptverfasser:	Föhr, Tiina, Waller, Katja, Viljanen, Anne, Rantanen, Taina, Kaprio, Jaakko, Ollikainen, Miina, Sillanpää, Elina
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Biomarkers Body mass index Chronic illnesses DNA methylation Epigenetics Mortality Physical activity Regression analysis THE JOURNAL OF GERONTOLOGY: Medical Sciences
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