Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies

Abstract Isolated rapid eye movement sleep behaviour disorder (iRBD) is a sleep disorder characterized by the loss of rapid eye movement sleep muscle atonia and the appearance of abnormal movements and vocalizations during rapid eye movement sleep. It is a strong marker of incipient synucleinopathy...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2023-08, Vol.146 (8), p.3301-3318
Hauptverfasser:	Rahayel, Shady, Tremblay, Christina, Vo, Andrew, Misic, Bratislav, Lehéricy, Stéphane, Arnulf, Isabelle, Vidailhet, Marie, Corvol, Jean-Christophe, Gagnon, Jean-François, Postuma, Ronald B, Montplaisir, Jacques, Lewis, Simon, Matar, Elie, Ehgoetz Martens, Kaylena, Borghammer, Per, Knudsen, Karoline, Hansen, Allan K, Monchi, Oury, Gan-Or, Ziv, Dagher, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - pathology Atrophy - pathology Cerebral Cortical Thinning - pathology Female Humans Life Sciences Male Mitochondria - metabolism Original REM Sleep Behavior Disorder - complications REM Sleep Behavior Disorder - diagnostic imaging REM Sleep Behavior Disorder - genetics Synucleinopathies - diagnostic imaging Synucleinopathies - genetics
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