Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017
During the Centers for Disease Control and Prevention's Zika Virus Response, birth defects surveillance programs adapted to monitor birth defects potentially related to Zika virus (ZIKV) infection during pregnancy. Pregnancy outcomes occurring during January 2016 to June 2017 in 22 U.S. states...
Gespeichert in:
| Veröffentlicht in: | Birth defects research 2022-08, Vol.114 (14), p.805-811 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 811 |
|---|---|
| container_issue | 14 |
| container_start_page | 805 |
| container_title | Birth defects research |
| container_volume | 114 |
| creator | Delaney, Augustina Olson, Samantha M. Roth, Nicole M. Cragan, Janet D. Godfred‐Cato, Shana Smoots, Ashley N. Fornoff, Jane Nestoridi, Eirini Eckert, Valorie Forkner, Allison Stolz, Amanda Crawford, Katherine Cho, Sook Ja Elmore, Amanda Langlois, Peter Nance, Amy Denson, Lindsay Forestieri, Nina Leedom, Vinita O. Tran, Tri Valencia‐Prado, Miguel Romitti, Paul Barton, Jerusha E. St. John, Kristen Mann, Sylvia Orantes, Lucia DeWilde, Leah Tong, Van T. Gilboa, Suzanne M. Moore, Cynthia A. Honein, Margaret A. |
| description | During the Centers for Disease Control and Prevention's Zika Virus Response, birth defects surveillance programs adapted to monitor birth defects potentially related to Zika virus (ZIKV) infection during pregnancy. Pregnancy outcomes occurring during January 2016 to June 2017 in 22 U.S. states and territories were used to estimate the prevalence of those brain and eye defects potentially related to ZIKV. Jurisdictions were divided into three groups: areas with widespread ZIKV transmission, areas with limited local ZIKV transmission, and areas without local ZIKV transmission. Prevalence estimates for selected brain and eye defects and microcephaly per 10,000 live births were estimated. Prevalence ratios (PRs) and 95% confidence intervals (CIs) were estimated using Poisson regression for areas with widespread and limited ZIKV transmission compared with areas without local ZIKV transmission. Defects with significantly higher prevalence in areas of widespread transmission were pooled, and PRs were calculated by quarter, comparing subsequent quarters to the first quarter (January–March 2016). Nine defects had significantly higher prevalence in areas of widespread transmission. The highest PRs were seen in intracranial calcifications (PR = 12.6, 95% CI [7.4, 21.3]), chorioretinal abnormalities (12.5 [7.1, 22.3]), brainstem abnormalities (9.3 [4.7, 18.4]), and cerebral/cortical atrophy (6.7 [4.2, 10.8]). The PR of the nine pooled defects was significantly higher in three quarters in areas with widespread transmission. The largest difference in prevalence was observed for defects consistently reported in infants with congenital ZIKV infection. Birth defects surveillance programs could consider monitoring a subset of birth defects potentially related to ZIKV in pregnancy. |
| doi_str_mv | 10.1002/bdr2.2067 |
| format | Article |
| fullrecord | <record><control><sourceid>wiley_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10391873</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>BDR22067</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4167-ada3ecd1f7c3765caf2397fa57223bdcbf2e2d63a77b2b2b065545e542911d2d3</originalsourceid><addsrcrecordid>eNp1kc9O3DAQhy3UChDlwAsgX5G6iz3exJtTxb_SIiSqFi5crIk9oW6Ds7KTRbn1yjvwdDxJE7YgOFQ-jEfz-bOtH2M7UkylELBfughTELleY5sw0zCRGvS7V_sNtp3SLyGEnIPUar7ONlRWiLwo5pvs4VukJdYULPGm4j44v_Suw5qXEX3gGBynnrijimyb-KJpKbQe67rnkWpsyfG24df-N_Klj10aFHwR6SZgsP3YADz-ub-a_pjy1A54elK2FKNvm-gpfeRnGDqMPQch81F21gUaG_2Bva-wTrT9r26xq88nl0dfJucXp1-PDs4ndiZzPUGHiqyTlbZK55nFClShK8w0gCqdLSsgcLlCrUsYlsizbJZRNoNCSgdObbFPK--iK2_J2eGHEWuziP52eJdp0Ju3k-B_mptmaaRQhZxrNRj2VgYbm5QiVS-HpTBjTGaMyYwxDezu69teyOdQBmB_Bdz5mvr_m8zh8Xd4Uv4Fe06e6A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Delaney, Augustina ; Olson, Samantha M. ; Roth, Nicole M. ; Cragan, Janet D. ; Godfred‐Cato, Shana ; Smoots, Ashley N. ; Fornoff, Jane ; Nestoridi, Eirini ; Eckert, Valorie ; Forkner, Allison ; Stolz, Amanda ; Crawford, Katherine ; Cho, Sook Ja ; Elmore, Amanda ; Langlois, Peter ; Nance, Amy ; Denson, Lindsay ; Forestieri, Nina ; Leedom, Vinita O. ; Tran, Tri ; Valencia‐Prado, Miguel ; Romitti, Paul ; Barton, Jerusha E. ; St. John, Kristen ; Mann, Sylvia ; Orantes, Lucia ; DeWilde, Leah ; Tong, Van T. ; Gilboa, Suzanne M. ; Moore, Cynthia A. ; Honein, Margaret A.</creator><creatorcontrib>Delaney, Augustina ; Olson, Samantha M. ; Roth, Nicole M. ; Cragan, Janet D. ; Godfred‐Cato, Shana ; Smoots, Ashley N. ; Fornoff, Jane ; Nestoridi, Eirini ; Eckert, Valorie ; Forkner, Allison ; Stolz, Amanda ; Crawford, Katherine ; Cho, Sook Ja ; Elmore, Amanda ; Langlois, Peter ; Nance, Amy ; Denson, Lindsay ; Forestieri, Nina ; Leedom, Vinita O. ; Tran, Tri ; Valencia‐Prado, Miguel ; Romitti, Paul ; Barton, Jerusha E. ; St. John, Kristen ; Mann, Sylvia ; Orantes, Lucia ; DeWilde, Leah ; Tong, Van T. ; Gilboa, Suzanne M. ; Moore, Cynthia A. ; Honein, Margaret A.</creatorcontrib><description>During the Centers for Disease Control and Prevention's Zika Virus Response, birth defects surveillance programs adapted to monitor birth defects potentially related to Zika virus (ZIKV) infection during pregnancy. Pregnancy outcomes occurring during January 2016 to June 2017 in 22 U.S. states and territories were used to estimate the prevalence of those brain and eye defects potentially related to ZIKV. Jurisdictions were divided into three groups: areas with widespread ZIKV transmission, areas with limited local ZIKV transmission, and areas without local ZIKV transmission. Prevalence estimates for selected brain and eye defects and microcephaly per 10,000 live births were estimated. Prevalence ratios (PRs) and 95% confidence intervals (CIs) were estimated using Poisson regression for areas with widespread and limited ZIKV transmission compared with areas without local ZIKV transmission. Defects with significantly higher prevalence in areas of widespread transmission were pooled, and PRs were calculated by quarter, comparing subsequent quarters to the first quarter (January–March 2016). Nine defects had significantly higher prevalence in areas of widespread transmission. The highest PRs were seen in intracranial calcifications (PR = 12.6, 95% CI [7.4, 21.3]), chorioretinal abnormalities (12.5 [7.1, 22.3]), brainstem abnormalities (9.3 [4.7, 18.4]), and cerebral/cortical atrophy (6.7 [4.2, 10.8]). The PR of the nine pooled defects was significantly higher in three quarters in areas with widespread transmission. The largest difference in prevalence was observed for defects consistently reported in infants with congenital ZIKV infection. Birth defects surveillance programs could consider monitoring a subset of birth defects potentially related to ZIKV in pregnancy.</description><identifier>ISSN: 2472-1727</identifier><identifier>EISSN: 2472-1727</identifier><identifier>DOI: 10.1002/bdr2.2067</identifier><identifier>PMID: 35906998</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>birth defects ; Brain - abnormalities ; Brain - virology ; Congenital Abnormalities - epidemiology ; Congenital Abnormalities - virology ; congenital Zika syndrome ; Eye Abnormalities - epidemiology ; Eye Abnormalities - virology ; Female ; Humans ; Infant ; Microcephaly ; population surveillance ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Prevalence ; Zika Virus ; Zika virus infection ; Zika Virus Infection - complications ; Zika Virus Infection - congenital ; Zika Virus Infection - epidemiology</subject><ispartof>Birth defects research, 2022-08, Vol.114 (14), p.805-811</ispartof><rights>Published 2022. This article is a U.S. Government work and is in the public domain in the USA.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4167-ada3ecd1f7c3765caf2397fa57223bdcbf2e2d63a77b2b2b065545e542911d2d3</citedby><cites>FETCH-LOGICAL-c4167-ada3ecd1f7c3765caf2397fa57223bdcbf2e2d63a77b2b2b065545e542911d2d3</cites><orcidid>0000-0001-6765-4963 ; 0000-0003-4224-2692 ; 0000-0002-4106-0953 ; 0000-0002-6279-5561 ; 0000-0001-5393-9984 ; 0000-0003-2627-7756 ; 0000-0003-0589-5766 ; 0000-0002-4326-890X ; 0000-0001-7894-0279</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbdr2.2067$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbdr2.2067$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35906998$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Delaney, Augustina</creatorcontrib><creatorcontrib>Olson, Samantha M.</creatorcontrib><creatorcontrib>Roth, Nicole M.</creatorcontrib><creatorcontrib>Cragan, Janet D.</creatorcontrib><creatorcontrib>Godfred‐Cato, Shana</creatorcontrib><creatorcontrib>Smoots, Ashley N.</creatorcontrib><creatorcontrib>Fornoff, Jane</creatorcontrib><creatorcontrib>Nestoridi, Eirini</creatorcontrib><creatorcontrib>Eckert, Valorie</creatorcontrib><creatorcontrib>Forkner, Allison</creatorcontrib><creatorcontrib>Stolz, Amanda</creatorcontrib><creatorcontrib>Crawford, Katherine</creatorcontrib><creatorcontrib>Cho, Sook Ja</creatorcontrib><creatorcontrib>Elmore, Amanda</creatorcontrib><creatorcontrib>Langlois, Peter</creatorcontrib><creatorcontrib>Nance, Amy</creatorcontrib><creatorcontrib>Denson, Lindsay</creatorcontrib><creatorcontrib>Forestieri, Nina</creatorcontrib><creatorcontrib>Leedom, Vinita O.</creatorcontrib><creatorcontrib>Tran, Tri</creatorcontrib><creatorcontrib>Valencia‐Prado, Miguel</creatorcontrib><creatorcontrib>Romitti, Paul</creatorcontrib><creatorcontrib>Barton, Jerusha E.</creatorcontrib><creatorcontrib>St. John, Kristen</creatorcontrib><creatorcontrib>Mann, Sylvia</creatorcontrib><creatorcontrib>Orantes, Lucia</creatorcontrib><creatorcontrib>DeWilde, Leah</creatorcontrib><creatorcontrib>Tong, Van T.</creatorcontrib><creatorcontrib>Gilboa, Suzanne M.</creatorcontrib><creatorcontrib>Moore, Cynthia A.</creatorcontrib><creatorcontrib>Honein, Margaret A.</creatorcontrib><title>Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017</title><title>Birth defects research</title><addtitle>Birth Defects Res</addtitle><description>During the Centers for Disease Control and Prevention's Zika Virus Response, birth defects surveillance programs adapted to monitor birth defects potentially related to Zika virus (ZIKV) infection during pregnancy. Pregnancy outcomes occurring during January 2016 to June 2017 in 22 U.S. states and territories were used to estimate the prevalence of those brain and eye defects potentially related to ZIKV. Jurisdictions were divided into three groups: areas with widespread ZIKV transmission, areas with limited local ZIKV transmission, and areas without local ZIKV transmission. Prevalence estimates for selected brain and eye defects and microcephaly per 10,000 live births were estimated. Prevalence ratios (PRs) and 95% confidence intervals (CIs) were estimated using Poisson regression for areas with widespread and limited ZIKV transmission compared with areas without local ZIKV transmission. Defects with significantly higher prevalence in areas of widespread transmission were pooled, and PRs were calculated by quarter, comparing subsequent quarters to the first quarter (January–March 2016). Nine defects had significantly higher prevalence in areas of widespread transmission. The highest PRs were seen in intracranial calcifications (PR = 12.6, 95% CI [7.4, 21.3]), chorioretinal abnormalities (12.5 [7.1, 22.3]), brainstem abnormalities (9.3 [4.7, 18.4]), and cerebral/cortical atrophy (6.7 [4.2, 10.8]). The PR of the nine pooled defects was significantly higher in three quarters in areas with widespread transmission. The largest difference in prevalence was observed for defects consistently reported in infants with congenital ZIKV infection. Birth defects surveillance programs could consider monitoring a subset of birth defects potentially related to ZIKV in pregnancy.</description><subject>birth defects</subject><subject>Brain - abnormalities</subject><subject>Brain - virology</subject><subject>Congenital Abnormalities - epidemiology</subject><subject>Congenital Abnormalities - virology</subject><subject>congenital Zika syndrome</subject><subject>Eye Abnormalities - epidemiology</subject><subject>Eye Abnormalities - virology</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Microcephaly</subject><subject>population surveillance</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Prevalence</subject><subject>Zika Virus</subject><subject>Zika virus infection</subject><subject>Zika Virus Infection - complications</subject><subject>Zika Virus Infection - congenital</subject><subject>Zika Virus Infection - epidemiology</subject><issn>2472-1727</issn><issn>2472-1727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9O3DAQhy3UChDlwAsgX5G6iz3exJtTxb_SIiSqFi5crIk9oW6Ds7KTRbn1yjvwdDxJE7YgOFQ-jEfz-bOtH2M7UkylELBfughTELleY5sw0zCRGvS7V_sNtp3SLyGEnIPUar7ONlRWiLwo5pvs4VukJdYULPGm4j44v_Suw5qXEX3gGBynnrijimyb-KJpKbQe67rnkWpsyfG24df-N_Klj10aFHwR6SZgsP3YADz-ub-a_pjy1A54elK2FKNvm-gpfeRnGDqMPQch81F21gUaG_2Bva-wTrT9r26xq88nl0dfJucXp1-PDs4ndiZzPUGHiqyTlbZK55nFClShK8w0gCqdLSsgcLlCrUsYlsizbJZRNoNCSgdObbFPK--iK2_J2eGHEWuziP52eJdp0Ju3k-B_mptmaaRQhZxrNRj2VgYbm5QiVS-HpTBjTGaMyYwxDezu69teyOdQBmB_Bdz5mvr_m8zh8Xd4Uv4Fe06e6A</recordid><startdate>20220815</startdate><enddate>20220815</enddate><creator>Delaney, Augustina</creator><creator>Olson, Samantha M.</creator><creator>Roth, Nicole M.</creator><creator>Cragan, Janet D.</creator><creator>Godfred‐Cato, Shana</creator><creator>Smoots, Ashley N.</creator><creator>Fornoff, Jane</creator><creator>Nestoridi, Eirini</creator><creator>Eckert, Valorie</creator><creator>Forkner, Allison</creator><creator>Stolz, Amanda</creator><creator>Crawford, Katherine</creator><creator>Cho, Sook Ja</creator><creator>Elmore, Amanda</creator><creator>Langlois, Peter</creator><creator>Nance, Amy</creator><creator>Denson, Lindsay</creator><creator>Forestieri, Nina</creator><creator>Leedom, Vinita O.</creator><creator>Tran, Tri</creator><creator>Valencia‐Prado, Miguel</creator><creator>Romitti, Paul</creator><creator>Barton, Jerusha E.</creator><creator>St. John, Kristen</creator><creator>Mann, Sylvia</creator><creator>Orantes, Lucia</creator><creator>DeWilde, Leah</creator><creator>Tong, Van T.</creator><creator>Gilboa, Suzanne M.</creator><creator>Moore, Cynthia A.</creator><creator>Honein, Margaret A.</creator><general>John Wiley & Sons, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6765-4963</orcidid><orcidid>https://orcid.org/0000-0003-4224-2692</orcidid><orcidid>https://orcid.org/0000-0002-4106-0953</orcidid><orcidid>https://orcid.org/0000-0002-6279-5561</orcidid><orcidid>https://orcid.org/0000-0001-5393-9984</orcidid><orcidid>https://orcid.org/0000-0003-2627-7756</orcidid><orcidid>https://orcid.org/0000-0003-0589-5766</orcidid><orcidid>https://orcid.org/0000-0002-4326-890X</orcidid><orcidid>https://orcid.org/0000-0001-7894-0279</orcidid></search><sort><creationdate>20220815</creationdate><title>Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017</title><author>Delaney, Augustina ; Olson, Samantha M. ; Roth, Nicole M. ; Cragan, Janet D. ; Godfred‐Cato, Shana ; Smoots, Ashley N. ; Fornoff, Jane ; Nestoridi, Eirini ; Eckert, Valorie ; Forkner, Allison ; Stolz, Amanda ; Crawford, Katherine ; Cho, Sook Ja ; Elmore, Amanda ; Langlois, Peter ; Nance, Amy ; Denson, Lindsay ; Forestieri, Nina ; Leedom, Vinita O. ; Tran, Tri ; Valencia‐Prado, Miguel ; Romitti, Paul ; Barton, Jerusha E. ; St. John, Kristen ; Mann, Sylvia ; Orantes, Lucia ; DeWilde, Leah ; Tong, Van T. ; Gilboa, Suzanne M. ; Moore, Cynthia A. ; Honein, Margaret A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4167-ada3ecd1f7c3765caf2397fa57223bdcbf2e2d63a77b2b2b065545e542911d2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>birth defects</topic><topic>Brain - abnormalities</topic><topic>Brain - virology</topic><topic>Congenital Abnormalities - epidemiology</topic><topic>Congenital Abnormalities - virology</topic><topic>congenital Zika syndrome</topic><topic>Eye Abnormalities - epidemiology</topic><topic>Eye Abnormalities - virology</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Microcephaly</topic><topic>population surveillance</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Prevalence</topic><topic>Zika Virus</topic><topic>Zika virus infection</topic><topic>Zika Virus Infection - complications</topic><topic>Zika Virus Infection - congenital</topic><topic>Zika Virus Infection - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Delaney, Augustina</creatorcontrib><creatorcontrib>Olson, Samantha M.</creatorcontrib><creatorcontrib>Roth, Nicole M.</creatorcontrib><creatorcontrib>Cragan, Janet D.</creatorcontrib><creatorcontrib>Godfred‐Cato, Shana</creatorcontrib><creatorcontrib>Smoots, Ashley N.</creatorcontrib><creatorcontrib>Fornoff, Jane</creatorcontrib><creatorcontrib>Nestoridi, Eirini</creatorcontrib><creatorcontrib>Eckert, Valorie</creatorcontrib><creatorcontrib>Forkner, Allison</creatorcontrib><creatorcontrib>Stolz, Amanda</creatorcontrib><creatorcontrib>Crawford, Katherine</creatorcontrib><creatorcontrib>Cho, Sook Ja</creatorcontrib><creatorcontrib>Elmore, Amanda</creatorcontrib><creatorcontrib>Langlois, Peter</creatorcontrib><creatorcontrib>Nance, Amy</creatorcontrib><creatorcontrib>Denson, Lindsay</creatorcontrib><creatorcontrib>Forestieri, Nina</creatorcontrib><creatorcontrib>Leedom, Vinita O.</creatorcontrib><creatorcontrib>Tran, Tri</creatorcontrib><creatorcontrib>Valencia‐Prado, Miguel</creatorcontrib><creatorcontrib>Romitti, Paul</creatorcontrib><creatorcontrib>Barton, Jerusha E.</creatorcontrib><creatorcontrib>St. John, Kristen</creatorcontrib><creatorcontrib>Mann, Sylvia</creatorcontrib><creatorcontrib>Orantes, Lucia</creatorcontrib><creatorcontrib>DeWilde, Leah</creatorcontrib><creatorcontrib>Tong, Van T.</creatorcontrib><creatorcontrib>Gilboa, Suzanne M.</creatorcontrib><creatorcontrib>Moore, Cynthia A.</creatorcontrib><creatorcontrib>Honein, Margaret A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Birth defects research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Delaney, Augustina</au><au>Olson, Samantha M.</au><au>Roth, Nicole M.</au><au>Cragan, Janet D.</au><au>Godfred‐Cato, Shana</au><au>Smoots, Ashley N.</au><au>Fornoff, Jane</au><au>Nestoridi, Eirini</au><au>Eckert, Valorie</au><au>Forkner, Allison</au><au>Stolz, Amanda</au><au>Crawford, Katherine</au><au>Cho, Sook Ja</au><au>Elmore, Amanda</au><au>Langlois, Peter</au><au>Nance, Amy</au><au>Denson, Lindsay</au><au>Forestieri, Nina</au><au>Leedom, Vinita O.</au><au>Tran, Tri</au><au>Valencia‐Prado, Miguel</au><au>Romitti, Paul</au><au>Barton, Jerusha E.</au><au>St. John, Kristen</au><au>Mann, Sylvia</au><au>Orantes, Lucia</au><au>DeWilde, Leah</au><au>Tong, Van T.</au><au>Gilboa, Suzanne M.</au><au>Moore, Cynthia A.</au><au>Honein, Margaret A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017</atitle><jtitle>Birth defects research</jtitle><addtitle>Birth Defects Res</addtitle><date>2022-08-15</date><risdate>2022</risdate><volume>114</volume><issue>14</issue><spage>805</spage><epage>811</epage><pages>805-811</pages><issn>2472-1727</issn><eissn>2472-1727</eissn><abstract>During the Centers for Disease Control and Prevention's Zika Virus Response, birth defects surveillance programs adapted to monitor birth defects potentially related to Zika virus (ZIKV) infection during pregnancy. Pregnancy outcomes occurring during January 2016 to June 2017 in 22 U.S. states and territories were used to estimate the prevalence of those brain and eye defects potentially related to ZIKV. Jurisdictions were divided into three groups: areas with widespread ZIKV transmission, areas with limited local ZIKV transmission, and areas without local ZIKV transmission. Prevalence estimates for selected brain and eye defects and microcephaly per 10,000 live births were estimated. Prevalence ratios (PRs) and 95% confidence intervals (CIs) were estimated using Poisson regression for areas with widespread and limited ZIKV transmission compared with areas without local ZIKV transmission. Defects with significantly higher prevalence in areas of widespread transmission were pooled, and PRs were calculated by quarter, comparing subsequent quarters to the first quarter (January–March 2016). Nine defects had significantly higher prevalence in areas of widespread transmission. The highest PRs were seen in intracranial calcifications (PR = 12.6, 95% CI [7.4, 21.3]), chorioretinal abnormalities (12.5 [7.1, 22.3]), brainstem abnormalities (9.3 [4.7, 18.4]), and cerebral/cortical atrophy (6.7 [4.2, 10.8]). The PR of the nine pooled defects was significantly higher in three quarters in areas with widespread transmission. The largest difference in prevalence was observed for defects consistently reported in infants with congenital ZIKV infection. Birth defects surveillance programs could consider monitoring a subset of birth defects potentially related to ZIKV in pregnancy.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>35906998</pmid><doi>10.1002/bdr2.2067</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-6765-4963</orcidid><orcidid>https://orcid.org/0000-0003-4224-2692</orcidid><orcidid>https://orcid.org/0000-0002-4106-0953</orcidid><orcidid>https://orcid.org/0000-0002-6279-5561</orcidid><orcidid>https://orcid.org/0000-0001-5393-9984</orcidid><orcidid>https://orcid.org/0000-0003-2627-7756</orcidid><orcidid>https://orcid.org/0000-0003-0589-5766</orcidid><orcidid>https://orcid.org/0000-0002-4326-890X</orcidid><orcidid>https://orcid.org/0000-0001-7894-0279</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2472-1727 |
| ispartof | Birth defects research, 2022-08, Vol.114 (14), p.805-811 |
| issn | 2472-1727 2472-1727 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10391873 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | birth defects Brain - abnormalities Brain - virology Congenital Abnormalities - epidemiology Congenital Abnormalities - virology congenital Zika syndrome Eye Abnormalities - epidemiology Eye Abnormalities - virology Female Humans Infant Microcephaly population surveillance Pregnancy Pregnancy Complications, Infectious - epidemiology Prevalence Zika Virus Zika virus infection Zika Virus Infection - complications Zika Virus Infection - congenital Zika Virus Infection - epidemiology |
| title | Prevalence of individual brain and eye defects potentially related to Zika virus in pregnancy in 22 U.S. states and territories, January 2016 to June 2017 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T08%3A00%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20individual%20brain%20and%20eye%20defects%20potentially%20related%20to%20Zika%20virus%20in%20pregnancy%20in%2022%E2%80%89U.S.%20states%20and%20territories,%20January%202016%20to%20June%202017&rft.jtitle=Birth%20defects%20research&rft.au=Delaney,%20Augustina&rft.date=2022-08-15&rft.volume=114&rft.issue=14&rft.spage=805&rft.epage=811&rft.pages=805-811&rft.issn=2472-1727&rft.eissn=2472-1727&rft_id=info:doi/10.1002/bdr2.2067&rft_dat=%3Cwiley_pubme%3EBDR22067%3C/wiley_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/35906998&rfr_iscdi=true |