Fibrotic Diseases of the Human Urinary and Genital Tract: Current Understanding and Potential Strategies for Treatment

Fibrosis is a disease condition characterized by abnormalities of the extracellular matrix, such as accumulation of the transforming growth factor β, infiltration by myofibroblasts, deposition of collagen, and a generalized dysregulation of collagen maturation. It can severely impair the function of...

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Veröffentlicht in:	Journal of clinical medicine 2023-07, Vol.12 (14), p.4770
Hauptverfasser:	Rahardjo, Harrina E, Märker, Viktoria, Tsikas, Dimitrios, Kuczyk, Markus A, Ückert, Stefan, Bannowsky, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Care and treatment Clinical medicine Collagen Cytokines Development and progression Diabetes Diabetic nephropathy Diagnosis Disease Extracellular matrix Fibroblasts Fibrosis Growth factors Inflammation Kinases MicroRNAs Oxidative stress Pathogenesis Proteins Review Smooth muscle Tumor necrosis factor-TNF Urogenital system
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