Exploring the Potential of a Genome-Reduced Escherichia coli Strain for Plasmid DNA Production

The global demand for nucleic acid-based vaccines, including plasmid DNA (pDNA) and mRNA vaccines, needs efficient production platforms. However, conventional hosts for plasmid production have encountered challenges related to sequence integrity due to the presence of insertion sequences (ISs). In t...

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Veröffentlicht in:	International journal of molecular sciences 2023-07, Vol.24 (14), p.11749
Hauptverfasser:	Nguyen, Thi Thuy, Bui, Le Minh, Byun, Ji-Young, Cho, Byung-Kwan, Kim, Sun Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Coronaviruses DNA E coli Escherichia coli - genetics Evolution & development Genes Genomes Glucose Mathematical models NADP - genetics Plasmids Plasmids - genetics Vaccines Vaccines, DNA - genetics
Online-Zugang:	Volltext
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