Cyclophilin A as a Pro-Inflammatory Factor Exhibits Embryotoxic and Teratogenic Effects during Fetal Organogenesis

The precise balance of Th1, Th2, and Th17 cytokines is a key factor in successful pregnancy and normal embryonic development. However, to date, not all humoral factors that regulate and influence physiological pregnancy have been completely studied. Our data here pointed out cyclophilin A (CypA) as...

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Veröffentlicht in:	International journal of molecular sciences 2023-07, Vol.24 (14), p.11279
Hauptverfasser:	Kalinina, Anastasiia, Semenova, Maria, Bruter, Alexandra, Varlamova, Ekaterina, Kubekina, Marina, Pavlenko, Natalia, Silaeva, Yulia, Deikin, Alexey, Antoshina, Elena, Gorkova, Tatyana, Trukhanova, Lubov, Salmina, Alla, Novikova, Svetlana, Voronkov, Dmitry, Kazansky, Dmitry, Khromykh, Ludmila
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Bones Cyclophilin A - genetics Cyclophilin A - metabolism Cytokines Developmental biology Embryonic development Embryos Female Females Fetus Fetus - metabolism Fetuses Genetic engineering Growth Health aspects Humans Immunology Mice Miscarriage Organogenesis Physiological aspects Physiology Preeclampsia Pregnancy Pregnancy Complications Pregnant women Signal Transduction Teratogenesis Transgenic animals
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