Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases

Thiamine (vitamin B1) is essential for the brain. This is attributed to the coenzyme role of thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine prodrug, the thioester benfotiamine (BFT), has been extensively studied and has beneficial effects both in rodent models o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2023-07, Vol.24 (14), p.11296
1. Verfasser:	Bettendorff, Lucien
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amyotrophic lateral sclerosis Animals Benfotiamine Biochemistry, biophysics & molecular biology Biochimie, biophysique & biologie moléculaire Biosynthesis Blood vessels Brain Catalysis Coenzymes Dehydrogenases Development and progression Enzymes Glucose Glucose metabolism Homeostasis Humans Life sciences Medical research Medicine, Experimental Metabolism Metabolites Mitochondria Nervous system diseases neuro-inflammation Neurodegenerative Diseases - drug therapy O,S-dibenzoylthiamine Oxidation Oxidative stress Phosphatase Physiological aspects Physiology Pyrimidines Review Sciences du vivant Thiamine - pharmacology Thiamine - therapeutic use Thiamine Pyrophosphate Vitamin B Vitamin deficiency
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!