Cancer progression by the okadaic acid class of tumor promoters and endogenous protein inhibitors of PP2A, SET and CIP2A

Purpose Okadaic acid class of tumor promoters are transformed into endogenous protein inhibitors of PP2A, SET, and CIP2A in human cancers. This indicates that inhibition of PP2A activity is a common mechanism of cancer progression in humans. It is important to study the roles of SET and CIP2A vis-à-...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2023-09, Vol.149 (11), p.9425-9433
Hauptverfasser:	Fujiki, Hirota, Sueoka, Eisaburo, Watanabe, Tatsuro, Komori, Atsumasa, Suganuma, Masami
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantigens - metabolism Breast cancer Cancer Cancer Research Carcinogens Carcinoma, Non-Small-Cell Lung - drug therapy Cell Line, Tumor Chronic myeloid leukemia Colorectal carcinoma Epidermal growth factor receptors Hematology Hepatocellular carcinoma Homeobox Humans Interleukin 1 Internal Medicine Intracellular Signaling Peptides and Proteins - genetics Liver Neoplasms Lung Neoplasms - drug therapy Male Medicine Medicine & Public Health Membrane Proteins - metabolism Myeloid leukemia Non-small cell lung carcinoma Okadaic Acid Oncology Pancreatic cancer Promoters Prostate cancer Radiation therapy Review Small cell lung carcinoma Tumor cells Tumor necrosis factor-α Tumors
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