Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1-Induced Cytopathicity

HIV-1 (HIV) infects CD4 T cells, the gradual depletion of which can lead to AIDS in the absence of antiretroviral therapy (ART). Some cells, however, survive HIV infection and persist as part of the latently infected reservoir that causes recurrent viremia after ART cessation. Improved understanding...

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Veröffentlicht in:	Journal of virology 2023-07, Vol.97 (7), p.e0065223
Hauptverfasser:	Vaidyanathan, Aparajitha, Taylor, Harry E, Hope, Thomas J, D'Aquila, Richard T, Bartom, Elizabeth T, Hultquist, Judd F, Peter, Marcus E
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular Response to Infection HIV Infections HIV-1 - physiology Humans MicroRNAs - genetics MicroRNAs - metabolism RNA-Induced Silencing Complex - metabolism Virus Latency - genetics
Online-Zugang:	Volltext
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