Determining the Predominant Conformations of Mortiamides A–D in Solution Using NMR Data and Molecular Modeling Tools

Macrocyclic peptidomimetics have been seriously contributing to our arsenal of drugs to combat diseases. The search for nature’s discoveries led us to mortiamides A–D (found in a novel fungus from Northern Canada), which is a family of cyclic peptides that clearly have demonstrated impressive pharma...

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Veröffentlicht in:ACS omega 2023-07, Vol.8 (29), p.25832-25838
Hauptverfasser: Franca, Tanos C. C., Goncalves, Arlan da Silva, Bérubé, Christopher, Voyer, Normand, Aubry, Norman, LaPlante, Steven R.
Format: Artikel
Sprache:eng
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