Lenalidomide-associated B-cell ALL: clinical and pathologic correlates and sensitivity to lenalidomide withdrawal

•Lenalidomide-associated B-ALL has high rates of TP53 mutation and hypodiploidy.•Combination chemotherapy, antigen-targeted therapies, and allogeneic transplantation are effective in achieving durable responses. [Display omitted] Lenalidomide is an effective component of induction and maintenance th...

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Veröffentlicht in:	Blood advances 2023-07, Vol.7 (13), p.3087-3098
Hauptverfasser:	Geyer, Mark B., Shaffer, Brian C., Bhatnagar, Bhavana, Mims, Alice S., Klein, Victoria, Dilip, Deepika, Glass, Jacob L., Lozanski, Gerard, Hassoun, Hani, Landau, Heather, Zhang, Yanming, Xiao, Wenbin, Roshal, Mikhail, Park, Jae H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Burkitt Lymphoma - drug therapy Hematopoietic Stem Cell Transplantation - adverse effects Humans Lenalidomide Lymphoid Neoplasia Multiple Myeloma - therapy Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Progression-Free Survival Retrospective Studies
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