Combinational expression of tumor testis antigens NY-ESO-1, MAGE-A3, and MAGE-A4 predicts response to immunotherapy in mucosal melanoma patients

Purpose Immunotherapy using immune checkpoint inhibitors (ICI) has revolutionized cancer treatment in recent years, particularly in melanoma. While response to immunotherapy is associated with high tumor mutational burden (TMB), PD-L1 expression, and microsatellite instability in several cancers, tu...

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Veröffentlicht in:Journal of cancer research and clinical oncology 2023-08, Vol.149 (9), p.5645-5653
Hauptverfasser: Freiberger, Sandra N., Holzmann, David, Morand, Grégoire B., Hüllner, Martin, Levesque, Mitchell P., Dummer, Reinhard, Koelzer, Viktor H., Rupp, Niels J.
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Sprache:eng
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