Cellular protection from H₂O₂ toxicity by Fv-Hsp70: protection via catalase and gamma-glutamyl-cysteine synthase

Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direct response to these stresses but in many situation...

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Veröffentlicht in:	Cell stress & chaperones 2023-07, Vol.28 (4), p.429-439
Hauptverfasser:	Hino, Chris, Chan, Grace, Jordaan, Gwen, Chang, Sophia S., Saunders, Jacquelyn T., Bashir, Mohammad T., Hansen, James E., Gera, Joseph, Weisbart, Richard H., Nishimura, Robert N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Catalase Cell Biology Cell death Cysteine synthase Heat shock proteins Hsp70 protein Hydrogen peroxide Hypoxia Immunology Ischemia Neurodegeneration Neurosciences Oxidation Oxidative stress SHORT COMMUNICATION Toxicity Toxins γ-Glutamylcysteine
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