SDC4-rs1981429 and ATM-rs228590 may provide early biomarkers of breast cancer risk

In Australia, 13% of women are diagnosed with breast cancer (BC) in their lifetime with approximately 20,000 women diagnosed with the disease in 2021. BC is characterised by complex histological and genomic influences with recent advances in cancer biology improving early diagnosis and personalised...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2023-07, Vol.149 (8), p.4563-4578
Hauptverfasser:	Vuorinen, Sofia I., Okolicsanyi, Rachel K., Gyimesi, Martina, Meyjes-Brown, Jacob, Saini, Deepa, Pham, Son H., Griffiths, Lyn R., Haupt, Larisa M.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein AKT1 protein Apoptosis Biomarkers Breast cancer Cancer Research Cell activation Cell differentiation Cell migration Cell surface Cell survival Diagnosis DNA damage DNA repair Extracellular matrix Gene expression Genomics Hematology Heparan sulfate Heparan sulfate proteoglycans Inositol Internal Medicine Kinases Medicine Medicine & Public Health Oncology Protein-serine/threonine kinase Single-nucleotide polymorphism Syndecan
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